Background: Cat-scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae and B. clarridgeiae. The typical manifestations of CSD include regional lymphadenitis and fever. However, CSD can have a wide variety of clinical manifestations that can lead to incorrect diagnoses and prolonged hospital stays.
Case Presentation: We present a case of a 3-year-old boy admitted to the pediatric service due to prolonged fever and abdominal pain. He received empirical antimicrobial treatment due to suspicion of infection. Abdominal ultrasound showed hepatosplenic abscesses. An IFA detected the presence of IgG antibodies against B. henselae (1:256). Patient was successfully treated with azithromycin and discharged after 7 weeks.
Conclusions: Hepatosplenic abscesses in CSD are rarely reported, particularly in immunocompetent children, with this, only 36 cases in PubMed, Web of Sciences and Scopus bibliographical databases. High rate of suspicion and serological tests availability are of utmost importance in order to detect it and treat it successfully and promptly.
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http://dx.doi.org/10.1186/s12941-019-0322-0 | DOI Listing |
Case Rep Infect Dis
August 2024
Division of Pediatric Infectious Disease University of Nebraska Medical Center, Omaha, NE, USA.
J Investig Med High Impact Case Rep
July 2024
Division of Infectious Diseases, Department of Medicine, Medical College of Georgia, Wellstar MCG Health, Augusta, GA, USA.
Eur J Clin Microbiol Infect Dis
August 2024
Department of Pediatrics, Division of Pediatric Infectious Diseases, Faculty of Medicine, Marmara University, Fevzi Cakmak, Muhsin Yazicioglu St, No:10, Floor: 6, Istanbul, Turkey.
Cat scratch disease (CSD) is an infection caused by Bartonella henselae, presents with non-specific symptoms like lymphadenopathy, fever, and fatigue. It can progress to disseminated disease, leading to complications such as liver and splenic micro abscesses, osteomyelitis, encephalitis, and uveitis. Diagnosis is challenging due to varied presentations and limited tests.
View Article and Find Full Text PDFJ Glob Infect Dis
October 2023
Department of Neurosurgery, Zibo Central Hospital, Zhangdian, Zibo, China.
Cureus
August 2023
Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PSE.
Chronic disseminated candidiasis (CDC) is a severe form of disseminated fungal infection that commonly affects the liver, spleen, and kidneys. In rare cases, CDC can be further complicated by an excessive immune response known as immune reconstitution inflammatory syndrome (IRIS). This syndrome occurs during the phase of immune recovery and is characterized by a systemic inflammatory response and excessive release of cytokines.
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