Purpose: To report a case of a 69-year-old patient who developed uveitis-glaucoma-hyphema syndrome (UGH) after an uneventful EX-PRESS mini shunt surgery for advanced primary open-angle glaucoma and to discuss management options and clinical implications. UGH syndrome is a rare, but serious complication usually described after cataract surgery. It is often described in anterior chamber intraocular lenses, sulcus lenses, and malpositioned or subluxed lenses resulting in chafing of the lens-iris interface. Clinical manifestations include increased intraocular pressure, anterior chamber inflammation, and recurrent hyphema.
Patient And Methods: We report a case of a 69-year-old African American man who developed UGH syndrome 8 years after uneventful implantation of a P-50 EX-PRESS miniature shunt. Slit-lamp examination demonstrated persistent inflammation without evidence of iris atrophy nor intraocular lens dislocation; however, gonioscopy demonstrated localized iris atrophy under the shunt with surrounding iris billowing and a layered hyphema.
Results: A localized laser iridoplasty around the shunt was performed leading to resolution of uveitis and hyphema. No other complications occurred during follow-up.
Conclusions: Given the increasing acceptance of glaucoma procedures involving implants, UGH syndrome may become more prevalent as new sources of intraocular devices may cause potential complications. Laser iridoplasty provides a minimally invasive approach to treating a localized source of chafing and reduce further surgical intervention.
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http://dx.doi.org/10.1097/IJG.0000000000001327 | DOI Listing |
Am J Ophthalmol Case Rep
December 2024
Capital Health, Trenton, NJ, USA.
Optic capture of a three-piece lens in the absence of posterior capsule support is an effective strategy for stabilizing and sequestering the optic to reduce the risk of dislocation and UGH syndrome compared to sulcus placement. We present a novel technique that facilitates optic capture in the presence of a contracted, fibrotic rhexis opening, while minimizing stress on the zonules by using iris retractors to assist in stabilization and expansion of the rhexis, followed by direct injection of the optic of the lens behind the anterior capsule opening into an optic captured configuration.
View Article and Find Full Text PDFWorld J Clin Cases
October 2024
Glaucoma and Cataract, Department of Ophthalmology, King Abdulaziz University Hospital, King Saud University, Riyadh 15112, Saudi Arabia.
Am J Ophthalmol Case Rep
December 2024
The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Purpose: To present a case of delayed recurrent hyphema following toric ICL implantation.
Observations: This case reports a 24-year-old Asian female who presented with sudden decrease in vision in the right eye, accompanied by recurrent massive anterior chamber hemorrhage, six months after bilateral implantation of toric ICL with central holes for myopia correction. Despite initial conservative treatment with immobilization and intraocular pressure (IOP)-lowering medication at another hospital, the hyphema persisted.
Am J Ophthalmol Case Rep
December 2024
Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Purpose: The Hydrus microstent was approved by the FDA in August 2018 for use with cataract surgery to reduce IOP in patients with mild to moderate primary open angle glaucoma (POAG). Pivotal clinical trials demonstrated its overall safety and efficacy in lowering IOP. However, malpositioning of the implant can result in uveitis-glaucoma-hyphema (UGH) syndrome necessitating device explantation.
View Article and Find Full Text PDFJ Glaucoma
November 2024
Department of Ophthalmology, Moran Eye Center, University of Utah, Salt Lake City, UT.
Uveitis-glaucoma-hyphema (UGH) syndrome is a rare condition characterized by intraocular inflammation, elevated intraocular pressure, and recurrent hyphema. Although UGH syndrome is typically caused by chafing between an intraocular lens and the iris or ciliary body, microinvasive glaucoma devices are becoming increasingly recognized as potential causes of recurrent intraocular inflammation. Herein, we discuss a case of UGH syndrome due to the subtle malposition of a Hydrus microstent that ultimately required surgical removal to manage.
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