Five new natural compounds (-) along with four known ones, involving dibenzo--pyrone derivatives, a benzo--pyrone derivative and an amide-type compound were obtained from , an endophyte isolated from The structures of these isolates were elucidated by intensive analysis of spectroscopic data including NMR, HRMS (ESI and EI), UV and IR spectra. Compounds (-) were evaluated for their cytotoxicities against five selected human tumourtumour cell lines (A-549, MDA-MB-231, MCF-7, KB and KB-VIN), and compound exhibited activities against MDA-MB-231and MCF-7 with IC values of 20.1 M and 32.2 M.
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http://dx.doi.org/10.1080/14786419.2019.1639699 | DOI Listing |
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