AI Article Synopsis
- * The study included 41 women with molar pregnancy, categorized into complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM), and matched them with 41 healthy pregnant women.
- * Findings showed a significant decrease in total and native thiol levels in molar pregnancy patients, indicating increased oxidative stress, but no significant difference was found in disulfide levels between CHM and PHM groups.
Article Abstract
: We aimed to investigate serum dynamic thiol and disulfide levels in patients with molar pregnancy (MP), and compare these concentrations with those of healthy pregnant women. Forty-one patients who were diagnosed with MP and 41 gestational age-matched healthy pregnant women were included in this prospective study. MP cases were separated in two groups as complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM). Demographic features and thiol/disulfide homeostasis were recorded for each woman. There was a significant correlation between the decrease in the total thiol and native thiol levels in MP patients. However, no significant difference was observed between CHM and PHM groups in terms of serum disulfide levels. OS is increased in MPs both in complete and partial moles, as determined by thiol/disulfide analysis.
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| http://dx.doi.org/10.1080/15513815.2019.1639090 | DOI Listing |
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