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| http://dx.doi.org/10.11604/pamj.2019.32.137.18274 | DOI Listing |
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Soft tissue tumours of the penis. The 30-year Istituto Nazionale Tumori di Milano experience.
Pathologica
February 2024
Pathology Unit, Azienda Ospedaliera di Bergamo, Bergamo, Italy.
Objective: Small series and individual cases of penile soft tissue tumours are reported in the literature: these are rare tumours that represent less than 5% of all penile tumours.
Methods: Penile soft tissue tumours were collected from the archive of the Department of Pathology at the Istituto Nazionale dei Tumori of Milan between January 1990 and October 2021. All available medical records were retrieved and reviewed to obtain clinical information.
Diagnostically Challenging Multifocal Penile Epithelioid Hemangioma Successfully Treated With Doxorubicin Hydrochloride.
Am J Dermatopathol
April 2024
Dermatology Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt; and.
Epithelioid hemangioma (EH), also known as angiolymphoid hyperplasia with eosinophilia, is an unusual vascular proliferation that tends to manifest in the head and neck region. Its occurrence on the penis is rare, with only scarce reported cases in the literature. The histopathological examination of this condition poses a challenge because it shares similarities with other entities, such as epithelioid hemangioendothelioma, epithelioid angiosarcoma, cutaneous epithelioid angiomatous nodule, or Kaposi sarcoma (KS).
View Article and Find Full Text PDFKaposi sarcoma of the penis successfully treated with oral propranolol.
Clin Exp Dermatol
August 2023
Dermatology Service, Miguel Servet University Hospital, Zaragoza, Spain.
PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples.
Cancer Biomark
February 2023
Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: Programmed death ligand 1 (PD-L1) is the target of immune checkpoint inhibitor therapies in a growing number of tumor types, but a unanimous picture on PD-L1 expression across cancer types is lacking.
Materials And Methods: We analyzed immunohistochemical PD-L1 expression in 11,838 samples from 118 human tumor types and its relationship with tumor infiltrating CD8 positive lymphocytes.
Results: At a cut-off level of 10% positive tumor cells, PD-L1 positivity was seen in 85 of 118 (72%) tumor types, including thymoma (100% positive), Hodgkin's lymphoma (93%), anaplastic thyroid carcinoma (76%), Kaposi sarcoma (71%), sarcomatoid urothelial carcinoma (71%), and squamous cell carcinoma of the penis (67%), cervix (65%), floor of the mouth (61%), the lung (53%), and pharynx (50%).
Thirteen cancers associated with HIV infection in a Black South African cancer patient population (1995-2016).
Int J Cancer
January 2023
Burden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa.
South Africa's HIV epidemic has evolved over time in terms of numbers of people living with HIV, access to antiretroviral treatment (ART) and age. These changes have profoundly influenced local cancer patterns. The Johannesburg Cancer Study has, over a period of 22 years (1995-2016), recruited over 20 000 incident black cancer patients who consented to provide answers to a questionnaire and blood samples (serum, DNA).
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