Previous studies have demonstrated a tactile Simon effect in which stimulus codes are generated based on the stimulated hand, not on limb position in external space (the somatotopic Simon effect). However, given evidence from visual Simon effect studies demonstrating that multiple stimulus codes can be generated for a single stimulus, we examined whether multiple stimulus codes can be generated for tactile stimuli as well. In our first experiment using four stimulators (two on each side of the hand), we found novel evidence for a hand-centered Simon effect, along with the typical somatotopic Simon effect. Next, we examined whether the potential salience of these somatotopic codes could be reduced, by testing only one hand with two stimulators attached. In Experiments 2-4, we found a strong hand-centered Simon effect with a diminished somatotopic Simon effect, providing evidence that stimulus salience can change the weighting of somatosensory stimulus coding. Finally, we also found novel evidence that the hand-centered Simon effect is coded in external, not somatotopic, coordinates. Furthermore, the diminished somatotopic Simon effect when testing on one hand only provides evidence that salience is an important factor in modulating the tactile Simon effect.
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http://dx.doi.org/10.1016/j.actpsy.2019.102874 | DOI Listing |
J Neurosci
March 2023
Department of Neurosciences and Movement Sciences, Section of Medicine, Faculty of Science and Medicine, University of Fribourg, CH-1700 Fribourg, Switzerland.
The premotor (PM) and primary motor (M1) cortical areas broadcast voluntary motor commands through multiple neuronal pathways, including the corticorubral projection that reaches the red nucleus (RN). However, the respective contribution of M1 and PM to corticorubral projections as well as changes induced by motor disorders or injuries are not known in nonhuman primates. Here, we quantified the density and topography of axonal endings of the corticorubral pathway in RN in intact monkeys, as well as in monkeys subjected to either cervical spinal cord injury (SCI), Parkinson's disease (PD)-like symptoms or primary motor cortex injury (MCI).
View Article and Find Full Text PDFNeuroimage
February 2022
Mood and Motor Control Laboratory, Boston, MA, United States; Laboratory of Neuroimaging and Genetics, United States; Martinos Center for Biomedical Imaging, United States; Departments of Neurology and Psychiatry, Charlestown, MA, United States. Electronic address:
The mammalian striatum is comprised of intermingled tissue compartments, matrix and striosome. Though indistinguishable by routine histological techniques, matrix and striosome have distinct embryologic origins, afferent/efferent connections, surface protein expression, intra-striatal location, susceptibilities to injury, and functional roles in a range of animal behaviors. Distinguishing the compartments previously required post-mortem tissue and/or genetic manipulation; we aimed to identify matrix/striosome non-invasively in living humans.
View Article and Find Full Text PDFActa Psychol (Amst)
July 2019
Department of Psychology, The University of Edinburgh, United Kingdom of Great Britain and Northern Ireland.
Previous studies have demonstrated a tactile Simon effect in which stimulus codes are generated based on the stimulated hand, not on limb position in external space (the somatotopic Simon effect). However, given evidence from visual Simon effect studies demonstrating that multiple stimulus codes can be generated for a single stimulus, we examined whether multiple stimulus codes can be generated for tactile stimuli as well. In our first experiment using four stimulators (two on each side of the hand), we found novel evidence for a hand-centered Simon effect, along with the typical somatotopic Simon effect.
View Article and Find Full Text PDFEur J Pain
April 2018
University Hospital Pain Center (CETD), Neurological Hospital P. Wertheimer, Hospices Civils de Lyon, France.
Background: The therapeutic influence of somatotopic matching between pain topography and motor cortex stimulation site for neuropathic pain (NP) remains controversial.
Methods: Thirty-two patients suffering from NP involving the upper limb (n = 20) or the face (n = 12) received two high-frequency rTMS neuronavigated sessions targeting hand and face motor cortical areas, versus placebo. The cortical target was defined by anatomical MRI and EMG responses in all patients, completed in 19 of them by functional MRI.
J Exp Psychol Hum Percept Perform
December 2014
Department of Cognitive Science, Johns Hopkins University.
Representing the locations of tactile stimulation can involve somatotopic reference frames in which locations are defined relative to a position on the skin surface, and also external reference frames that take into account stimulus position in external space. Locations in somatotopic and external reference frames can conflict in terms of left/right assignment when the hands are crossed or positioned outside of their typical hemispace. To investigate the spatial codes of the representation of both tactile stimuli and responses to touch, a Simon effect task, often used in the visual modality to examine issues of spatial reference frames, was deployed in the tactile modality.
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