Metal nanoprobes have recently attracted board research interestinr their application in establishing sensing systems due to their unique optical, electrical, physical, and chemical properties. In comparison to gold and silver nanoprobes, analytical platform based on copper nanoprobes (Cu-NPs) is still in the early stages of development. In this review, we focus on single-stranded, and double-stranded DNA capped Cu-NPs sensing systems which have been designed for various analytes, including metal ions, anions, small molecules, biomolecules (DNA, RNA, and protein, etc.). In addition, the application of Cu-NPs in biological labeling or bio-imaging platforms has also been introduced and summarized.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/tcr.201900022 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tb-based Metal-Organic Framework-Referenced Fluorescence Assay for Distinguishing Hydroquinone from Its Isomers and Subsequent Quantitative Visual Detection of Cu.
Anal Chem
January 2025
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Hydroquinone (HQ) and copper ions (Cu) are categorized as environmental pollutants that are severely limited in water. Designing a selective assay for discriminating HQ from its two isomers and the convenient determination of Cu is of great importance. Herein, a Tb-based metal-organic framework (Tb-MOF) and HQ are assembled innovatively into a ratiometric fluorescence nanoprobe to selectively distinguish HQ and subsequent quantitative visual detection of Cu.
View Article and Find Full Text PDFA Near-Infrared-II Fluorescent Nanoprobe Offering Real-Time Tracking of Fenton-Like Reaction for Cancer Chemodynamic Theranostics.
Nano Lett
January 2025
School of Pharmacy, Minhang Hospital, Key Laboratory of Smart Drug Delivery Ministry of Education, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, P.R. China.
Chemodynamic therapy (CDT) utilizing Fenton or Fenton-like reactions to generate cytotoxic hydroxyl radicals by metal ions has become a compelling strategy for cancer treatment. Visualizing intratumoral Fenton or Fenton-like reactions especially at a cellular level in real-time can directly monitor the process of CDT, which is not yet feasible. Here, we present a molecule BADA chelating Cu to form Cu-BADA nanoparticles, exhibiting fluorescence quenching properties through intermolecular electron transfer.
View Article and Find Full Text PDFA new molecularly imprinted nanocatalytic probe for RRS determination of trace enrofloxacin based on covalent organic framework polymer.
J Colloid Interface Sci
March 2025
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China; Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China; Guangxi Key Laboratory of Environmental Processes and Remediation in Ecologically Fragile Regions, Guilin 541004, China. Electronic address:
A new nanopalladium surface molecularly imprinted covalent organic framework (MICOF) catalytic probe (Pd@TpPa) for enrofloxacin (ENR) was synthesized by molecular imprinting technology, using 1,3,5-triformylphloroglucinol (Tp) and p-phenylenediamine (Pa) as monomers, ENR as the template molecule, and palladium nanoparticles (PdNP) as the core of nanocatalytic probe. This nanoprobe not only specifically recognizes ENR but also catalyzes the cupric tartrate-glucose (GL) indicator reaction. The amino groups in TpPa replace the tartrate ions, forming a new complex with Cu.
View Article and Find Full Text PDFGold metallene-based ECL biosensor to detect miRNA-126 for coronary artery calcification diagnosis.
Biosens Bioelectron
March 2025
Department of Cardiovascular Medicine, China-Japan Union Hospital of Jilin University, Changchun, 130033, China. Electronic address:
Coronary artery calcification (CAC) is a pathological change and independent risk factor in cardiovascular diseases. In this work, a gold-based metallene structure was prepared as sensing interface based on mPEG-SH modified Au nanoparticles for the CAC detection. Firstly, a novel nanovesicle was self-assembled with excellent conductivity.
View Article and Find Full Text PDFUnveiling the spatial rearrangements of exhausted immobilised multi-enzyme systems through cryo-X-ray fluorescence nanoprobe imaging.
Chem Sci
December 2024
Ikerbasque, Basque Foundation for Science Plaza Euskadi 5 Bilbao 48009 Spain.
Article Synopsis
- Enzyme immobilisation is crucial for creating stable biocatalysts that can be reused, but the behavior of enzymes on solid supports, especially under operational conditions, is not fully understood.
- X-ray fluorescence imaging was used to study structural changes in a biocatalyst made from two unmodified metalloenzymes (laccase and dehydrogenase) when exposed to high temperatures or other operational conditions.
- Findings reveal that while both protein and metal components rearrange during usage, they move as a unit, causing minor structural changes but leading to the biocatalyst's eventual exhaustion, highlighting the need for better understanding using advanced imaging techniques for improved bioprocesses.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!