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Association of resistin rs1862513, rs10401670 and rs3745367 polymorphisms with resistin level and insulin resistance in an Iranian type 2 diabetic population.
J Diabetes Metab Disord
June 2025
Department of Biology, Islamshahr Branch, Islamic Azad University, Islamshahr, Tehran, Iran.
Objectives: The study investigates the association of single nucleotide polymorphisms (SNP) in resistin gene (RETN) with resistin level, insulin resistance, and the risk of type 2 diabetes in an early diagnosed type 2 diabetic population of Iran.
Methods: The total of 80 healthy subjects and 80 individuals diagnosed with type 2 diabetes. To ascertain the genotypes of rs1862513 and rs3745367, we performed the polymerase chain reaction with restriction fragment length polymorphism (PCR-RFLP) technique.
The Influence of Body Composition, Lifestyle, and Dietary Components on Adiponectin and Resistin Levels and AR Index in Obese Individuals.
Int J Mol Sci
January 2025
Department of Human Immunology, Institute of Medical Sciences, Medical College of Rzeszow University, University of Rzeszow, 35-959 Rzeszow, Poland.
Adipose tissue of obese people secretes a number of adipokines, including adiponectin and resistin, which have an antagonistic effect on the human metabolism, influencing the pathogenesis of many diseases based on low-grade inflammation. Body composition analysis using bioelectrical impedance analysis (BIA) was performed in 84 adults with obesity, i.e.
View Article and Find Full Text PDFAdipokines and Gamma-Glutamyl Transferase as Biomarkers of Metabolic Syndrome Risk in Mexican School-Aged Children.
Nutrients
December 2024
Facultad de Salud Pública y Nutrición (FaSPyN), Universidad Autónoma de Nuevo León (UANL), Monterrey 64460, Nuevo León, Mexico.
: The prevalence of metabolic syndrome in children has been increasing, raising concerns about early detection and clinical management. Adipokines, which are secreted by adipose tissue, play a critical role in metabolic regulation and inflammation, while gamma-glutamyl transferase (GGT), as a liver enzyme, is linked to oxidative stress and metabolic disorders. The objective was to examine the association of circulating adipokines and GGT with metabolic syndrome risk in school-aged children from Northeast Mexico.
View Article and Find Full Text PDFCould Selected Adipokines/Cytokines Serve as Markers of Adipose Tissue Dysfunction?
Int J Mol Sci
December 2024
Department of Biostatistics and Medical Informatics, Medical University of Bialystok, ul. Szpitalna 37, 15-295 Bialystok, Poland.
Elevated levels of pro-inflammatory adipokines and cytokines increase the risk of developing metabolic disorders and diseases. The aim of this study was to conduct a comparative analysis of selected adipokines/cytokines in the blood serum of adults with obesity and normal body weight. The study also evaluated the correlation of these adipokines/cytokines with selected biochemical blood parameters.
View Article and Find Full Text PDFBody Composition, Adipocytokine, and Metabolic Parameters in Men With Congenital Hypogonadotropic Hypogonadism.
Clin Endocrinol (Oxf)
January 2025
Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objective: This study aimed to evaluate the long-term effects of hormone therapies on the body composition, adipokines and metabolic parameters of adult men with congenital hypogonadotropic hypogonadism (CHH).
Methods: Sixty-six patients with CHH and 21 healthy controls were recruited. Patients were divided into untreated (n = 33) and treated (n = 33) groups based on hormone therapy history.
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