Serum levels of progesterone, cortisol and phenytoin as well as the excretion of 17-OHCS were determined in 45 male epileptics before and during 24 months of the therapy. A significant decrease of the hormones was found in untreated patients. Phenytoin administration caused further decrease of cortisol and its metabolite 17-OHCS levels and a compensation of progesterone serum concentration.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1032863 | PMC |
| http://dx.doi.org/10.1136/jnnp.51.3.374 | DOI Listing |
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