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A Comprehensive Review Highlighting the Prospects of Phytonutrient Berberine as an Anticancer Agent.
J Biochem Mol Toxicol
January 2025
Department of Translational Medicine, Clinical Research Centre, Skåne University Hospital, Lund University, Malmö, Sweden.
Berberine, an isoquinoline alkaloid derived from various medicinal plants, emerges as a potential therapeutic agent against diverse human diseases. It has particularly shown notable anticancer efficacy against breast, colorectal, lung, prostate, and liver cancer. Berberine results in inhibition of cancer cell proliferation, induction of apoptosis, and suppressing angiogenesis, positioning it as a versatile, multitargeted therapeutic tool against cancer.
View Article and Find Full Text PDFHigh-throughput near-infrared spectroscopy for detection of major components and quality grading of peas.
Front Nutr
December 2024
Key Laboratory of Geriatric Nutrition and Health, Ministry of Education (Beijing Technology and Business University), Beijing, China.
Pea ( L.) is a nutrient-dense legume whose nutritional indicators influence its functional qualities. Traditional methods to identify these components and examine the relationships between their contents could be more laborious, hindering the quality assessment of the varieties of peas.
View Article and Find Full Text PDFThe 2023 report of the synergetic roadmap on carbon neutrality and clean air for China: Carbon reduction, pollution mitigation, greening, and growth.
Environ Sci Ecotechnol
January 2025
State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing, 100084, China.
The response to climate change and air pollution control demonstrates strong synergy across scientific mechanisms, targets, strategies, and governance systems. This report, based on a monitoring indicator system for coordinated governance of air pollution and climate change, employs an interdisciplinary approach combining natural and social sciences. It establishes 20 indicators across five key areas: air pollution and climate change, governance systems and practices, structural transformation and technologies, atmospheric components and emission reduction pathways, and health impacts and co-benefits.
View Article and Find Full Text PDFDiminished Returns of Educational Attainment on Numeracy Score of Latino Populations: Insights from UAS Data.
Open J Neurosci
November 2024
Department of Neurology, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Background: Educational attainment is a well-established social determinant of various domains of cognitive function across the lifespan. However, the theory of Minorities' Diminished Returns (MDRs) suggests that the health benefits of educational attainment tend to be weaker for ethnic minorities compared to non-Latino Whites. This phenomenon may reflect the impact of structural inequalities, social stratification, and historical disadvantage.
View Article and Find Full Text PDFPoloxamer 188 stabilized poly (ε-caprolactone) microspheres of voriconazole for targeting pulmonary aspergillosis.
Ther Deliv
December 2024
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India.
Aim: Voriconazole (VRZ) is highly effective in treating invasive pulmonary aspergillosis (IPA), in addition to hepatotoxicity. Therefore, the current study focuses on the development and characterization of voriconazole-loaded microspheres (VRZ@PCL MSPs) to augment pulmonary localization and antifungal efficacy.
Methods: VRZ@PCL MSPs were fabricated by using the o/w emulsion method.
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