AI Article Synopsis
- ICU delirium significantly affects patient outcomes in terms of mortality, length of hospital stay, and costs, often worsened by the withdrawal from home psychotropic medications during ICU admission.
- A retrospective chart review of 2334 patients found no significant difference in the use of new antipsychotics, restraint use, or ICU length of stay when comparing groups, but there was a notable decrease in overall hospital stay duration.
- The findings suggest that reinitiating psychotropic medications early in the ICU setting can help reduce hospital length of stay but does not impact the need for new antipsychotic treatments or restraint use.
Article Abstract
Introduction: Intensive care unit (ICU) delirium is a major contributing factor to increased mortality, length of stay, and cost of care. Psychotropic medications may often require extensive tapering to prevent withdrawal symptoms; during ICU admission, home psychotropics are frequently held which may precipitate acute drug withdrawal and subsequent delirium.
Methods: This is a single-center, observational, retrospective chart review. The primary endpoint was the total number of new-start antipsychotics used to treat ICU delirium. Secondary endpoints included use of restraints, ICU length of stay, and hospital length of stay.
Results: A total of 2334 charts were reviewed for inclusion; 55 patients were categorized into each group. There was no statistically significant difference in the requirement for new-start antipsychotics ( = 1.0), restraint use ( = .057), or ICU length of stay ( = .71). There was a statistically significant decrease in hospital length of stay ( = .048).
Discussion: Early reinitiation was associated with a decrease in hospital length of stay but was not associated with a decrease in the number of new-start antipsychotics, use of restraints, or ICU length of stay.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607949 | PMC |
| http://dx.doi.org/10.9740/mhc.2019.07.263 | DOI Listing |
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