Cytotoxic phenolic compounds isolated from the fruits of .

Nat Prod Res

Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi, Vietnam.

Published: June 2021

A new modified geranylated flavonoid, 3'-dehydroxy-solophenol C (), along with 17 known compounds (-) were isolated from the fruits of . Their structures were established by spectral analysis, such as mass spectrometry, 1D-NMR and 2D-NMR. The new geranylated flavonoid showed a moderate cytotoxic activity against the A549 cell line with IC value of 16.0 µM. Compound showed the highest cytotoxic activities against KB, HepG2, Lu-1 and MCF7 cell lines with IC values of 0.6, 0.8, 1.3 and 1.2 µM, respectively.

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http://dx.doi.org/10.1080/14786419.2019.1639175DOI Listing

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