Cell Polarity: Getting the PARty Started. | LitMetric

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Cell Polarity: Getting the PARty Started. | LitMetric

Cell Polarity: Getting the PARty Started.

Mike Boxem Sander van den Heuvel

Curr Biol

Developmental Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands. Electronic address:

Published: July 2019

Polarity establishment is a key developmental process, but what determines its timing is poorly understood. New research in Caenorhabditis elegans demonstrates that the PAR polarity system extensively reconfigures before becoming competent to polarize. By inhibiting membrane localization of anterior PAR proteins, AIR-1 (aurora A) and PLK-1 (polo kinase) prevent premature polarization.

Download full-text PDF	Source
http://dx.doi.org/10.1016/j.cub.2019.05.032	DOI Listing

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