A FRET probe for the detection of alkylating agents.

Chem Commun (Camb)

CEA-Université Paris-Saclay, Institut Joliot, Service de Chimie Bioorganique et de Marquage, Bât. 547, 91191 Gif-sur-Yvette, France. frederic.taran.cea.fr

Published: July 2019

Herein, we describe a new strategy for the detection of reactive alkylating agents such as alkyl halides. These toxic compounds react with a FRET-based profluorescent probe, triggering a self-immolative elimination at room temperature, thus leading to a fluorescence signal.

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Source
http://dx.doi.org/10.1039/c9cc04391hDOI Listing

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