AI Article Synopsis
- Identification of Fabry disease (FD) in cardiac patients has mainly focused on those with left ventricular hypertrophy.
- The study investigated 188 patients under 70 with conduction issues needing pacemakers and found no cases of FD.
- As classical signs of FD were present but no actual diagnoses were made, screening for FD in this group is not recommended.
Article Abstract
Identification of Fabry disease (FD) in cardiac patients has been restricted so far to patients with left ventricular hypertrophy. Conduction problems are frequent in FD and could precede other manifestations, offering a possible earlier diagnosis.We studied the prevalence of FD in 188 patients < 70 years with conduction problems requiring pacemaker implantation. Although classical manifestations of FD were not rare, no patient with FD was identified. Screening efforts should not be conducted in this population.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615152 | PMC |
| http://dx.doi.org/10.1186/s13023-019-1140-3 | DOI Listing |
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