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Formulation of minitablets with personalised dissolution profile by fluid-bed granulation ofdrug nanosuspensions.
Int J Pharm
January 2025
Department of Chemical Engineering, University of Chemistry and Technology Prague, Technická 5, Prague 6, 16628, Czech Republic. Electronic address:
Transforming poorly soluble active pharmaceutical ingredients (APIs) into a nanoparticulate form is a proven way of improving their dissolution characteristics. The preparation of API nanosuspensions is commonly achieved by wet-stirred media milling. The challenge lies in converting the nanosuspension into a solid dosage form without compromising its re-dispersibility.
View Article and Find Full Text PDFScalable mesoporous biochars from bagasse waste for Cu (II) removal: Process optimisation, kinetics and techno-economic analysis.
J Environ Manage
November 2024
School of Engineering, Chemical Engineering, University of Hull, Hull, HU6 7RX, United Kingdom. Electronic address:
As the world faces the brink of climatological disaster, it is crucial to utilize all available resources to facilitate environmental remediation, especially by accommodating waste streams. Lignocellulosic waste residues can be transformed into mesoporous biochar structures with substantial pore capacity. While biochars are considered a method of carbon dioxide removal (CDR), they are in fact an environmental double-edged sword that can be used to extract metal ions from water bodies.
View Article and Find Full Text PDFExploring the evolution of bacterial cellulose precursors and their potential use as cellulose-based building blocks.
Sci Rep
May 2024
Department of Chemical, Materials and Industrial Production Engineering, University of Naples Federico II, Naples, Italy.
Article Synopsis
- Natural polymers are being used more because they are less harmful, and bacterial cellulose is a really good example because it works well for medical uses.
- This study focused on understanding the tiny structure of bacterial cellulose from a special mix of bacteria and yeast called SCOBY, using advanced microscopes.
- We found that the structure changes as it rises in a liquid, and we can measure these changes without needing complex prep work, showing that SCOBY can create unique cellulose materials for different uses.
Rheological and dielectric behavior of sodium carboxymethyl cellulose (NaCMC)/Ca and esterified NaCMC/Ca hydrogels: Correlating microstructure and dynamics with properties.
Carbohydr Polym
July 2024
Department of Physics, Dr. Harisingh University, Sagar 470003, Madhya Pradesh, India.
Polyelectrolyte-based conductive hydrogels are being extensively explored for applications in energy storage and as electrode materials for batteries. We synthesized ionically crosslinked sodium carboxymethyl cellulose (NaCMC), esterified NaCMC, and Ca doped esterified NaCMC hydrogels. This work aims to understand the effect of Ca ions on the NaCMC and esterified NaCMC.
View Article and Find Full Text PDFCreating and exploring carboxymethyl cellulose aerogels as drug delivery devices.
Carbohydr Polym
May 2024
Mines Paris, PSL University, Center for Materials Forming (CEMEF), UMR CNRS 7635, CS 10207, Rue Claude Daunesse, 06904 Sophia Antipolis, France. Electronic address:
Carboxymethyl cellulose (CMC) is a well-known cellulose derivative used in biomedical applications due to its biocompatibility and biodegradability. In this work, novel porous CMC materials, aerogels, were prepared and tested as a drug delivery device. CMC aerogels were made from CMC solutions, followed by non-solvent induced phase separation and drying with supercritical CO.
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