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We report a rare case of concurrent onset of osimertinib-induced heart failure and metronidazole-induced encephalopathy during treatment of a brain abscess. A 78-year-old female with lung adenocarcinoma presented with neurological symptoms and was diagnosed with a brain abscess. During treatment, she developed heart failure and encephalopathy, linked to osimertinib and metronidazole, respectively.

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Cerebral abscess due to hematogenous spread originating from a urinary infection is a rare condition. This clinical case involves an 80-year-old woman with a history of recurrent urinary infections. She presented to the emergency department with fever and altered consciousness.

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Cerebral cavernous malformations (CCMs) are angiographically occult vascular lesions that present with a variety of neurological symptoms, including seizures, features of raised intracranial pressure and focal neurological deficits. In extremely rare circumstances, CCMs have presented with concomitant brain abscess formation. To date, five cases have previously been reported, the majority of which have affected patients aged 16 years or older.

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Diagnostic role of sonography in early detection and surgical intervention of an epidural abscess: A case report.

Australas J Ultrasound Med

November 2024

Argentinian Critical Care Ultrasonography Association (ASARUC) Buenos Aires C1424FSD Argentina.

Introduction: Intracranial epidural abscesses require swift diagnosis and treatment. While magnetic resonance imaging (MRI) is preferred for its detailed visualisation, it is costly and time-consuming. Transcranial sonography offers a rapid, portable and cost-effective alternative for assessing brain lesions.

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Clinical features and outcome of brain abscess after introduction of CT and MRI: A meta-analysis.

J Infect

December 2024

European Society of Clinical Microbiology and Infectious Diseases, Study Group for Infections of the Brain (ESGIB), Basel, Switzerland; Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Objective: To describe the clinical features and outcome of brain abscess since introduction of computerized tomography and magnetic resonance imaging.

Methods: MEDLINE and Embase were searched using "brain abscess" or "cerebral abscess" from 1970 through 2023 and analyses restricted to study populations hospitalized after 1980. Single-variable meta-analyses were done using a random-effects model.

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