Eight undescribed 9,19-cycloartane type triterpenoid glycosides (cimdalglnoside A-H) and ten known analogues were obtained from the phytochemical research on the roots of Actaea dahurica (syn. Cimicifuga dahurica). All compounds were characterised by spectroscopic experiments, and chemical method. All the compounds isolated were assayed for cytotoxicity to five human cancer cell lines. Cimdalglnoside G showed promising cytotoxicities against Hela, and MCF-7 cell lines with IC values at 7.7 and 12.2 μM.
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http://dx.doi.org/10.1016/j.fitote.2019.104262 | DOI Listing |
J AOAC Int
March 2024
American Herbal Pharmacopoeia, 3051 Brown's Lane, Soquel, CA 95073, USA.
Nat Prod Res
January 2023
School of Material Science and Engineering, Anhui University of Technology, Maanshan, P.R. China.
Two new cycloartane triterpenoid glycosides, soulieoside V () and 15-deacetylbeesioside O (), together with one known compound, beesioside J (), were isolated from the ethanolic extract of the rhizomes of . Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. All the compounds were tested for their cytotoxic activities against human cancer cell lines.
View Article and Find Full Text PDFPhytomedicine
December 2020
Department of Pharmaceutical Chemistry, University of Vienna, 1090 Vienna, Austria; Vienna Metabolomics Center (VIME), University of Vienna, 1090 Vienna, Austria. Electronic address:
Background: Actaea racemosa L., also known as black cohosh, is a popular herb commonly used for the treatment of menopausal symptoms. Because of its purported estrogenic activity, black cohosh root extract (BCE) may trigger breast cancer growth.
View Article and Find Full Text PDFZ Naturforsch C J Biosci
September 2021
Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, 147 002, Punjab, India.
The methanol extract and its ethyl acetate fraction (EAF) of (Wall. ex. Royle) H.
View Article and Find Full Text PDFNat Prod Res
April 2022
Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
A new phenylpropanoid allopyranoside () and a new indolinone alkaloid () were isolated from the rhizomes of (syn. ). The structures of those two compounds were deduced as cimicifugaside F () and 3,11-(3-methyl-2-butenylidene acid)-2-indolinone-1---d-glucopyranoside () by detailed analysis of their MS, 1D and 2D NMR data and comparison with literatures.
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