Background: Starch nanoparticles have become among the most interesting nanovehicles for drug delivery because of their relatively easy synthesis, biocompatibility, and numerous botanical sources. Starch nanoparticles obtained from green bananas were cross-linked with citric acid and loaded with β-carotene.
Results: Mean particle size, encapsulation efficiency, and β-carotene release in simulated gastric and intestinal fluids and food simulants were studied. Cross-linked nanoparticles showed higher loading efficiency and encapsulation capacity, indicating that they can accommodate more molecules than their unmodified counterparts, while mathematical models showed a diffusion of released β-carotene into food simulant media.
Conclusions: Cross-linked nanoparticles showed more controlled release under gastric conditions, mainly in the simulated intestinal fluid, indicating that they are suitable as vehicles for intestine-specific targeting. This controlled released was also observed in food simulants, with lower release values in the more aqueous simulants. © 2019 Society of Chemical Industry.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jsfa.9918 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Preparation, characterization, and antibacterial application of cross-linked nanoparticles composite films.
Food Chem X
January 2025
Key Laboratory of Ministry of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.
This study aimed to prepare a composite film by blending cross-linked tapioca starch (CLTS) with sodium alginate (SA), silver nanoparticles (AgNPs), and ZnO nanoparticles (ZnOs). The effects of SA, AgNPs, and ZnOs at different concentrations (1-3 wt%) on the mechanical properties, optical properties, thermal stability, and antibacterial activity of cross-linked starch films were also investigated. The structures of the films were examined by Fourier transform infrared spectroscopy and X-ray diffraction.
View Article and Find Full Text PDFComprehensive Sensory Evaluation in Low-Fat Emulsions: A Systematic Review of Diverse Food Applications.
Food Sci Nutr
January 2025
The prevalence of diet-related health issues has driven the demand for healthier food options, particularly those with reduced fat content. This systematic review evaluates the integration of sensory analysis in low-fat emulsion research, highlighting a significant gap in current practices. From an initial pool of 400 articles, 227 unique studies were screened, but only 15 (6.
View Article and Find Full Text PDFClick Chemistry as an Efficient Toolbox for Coupling Sterically Hindered Molecular Systems to Obtain Advanced Materials for Nanomedicine.
Int J Mol Sci
December 2024
Materials Research Institute, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Since its conceptualization, click chemistry in all its variants has proven to be a superior synthesis protocol, compared to conventional methods, for forming new covalent bonds under mild conditions, orthogonally, and with high yields. If a term like reactive resilience could be established, click reactions would be good examples, as they perform better under increasingly challenging conditions. Particularly, highly hindered couplings that perform poorly with conventional chemistry protocols-such as those used to conjugate biomacromolecules (e.
View Article and Find Full Text PDFReview of the Synthesis and Degradation Mechanisms of Some Biodegradable Polymers in Natural Environments.
Polymers (Basel)
December 2024
Fujian Special Equipment Inspection and Research Institute, Fuzhou 350008, China.
The escalating demand for sustainable materials has been fueling the rapid proliferation of the biopolymer market. Biodegradable polymers within natural habitats predominantly undergo degradation mediated by microorganisms. These microorganisms secrete enzymes that cleave long-chain polymers into smaller fragments for metabolic assimilation.
View Article and Find Full Text PDFRecent Advances on Starch-Based Adsorbents for Heavy Metal and Emerging Pollutant Remediation.
Polymers (Basel)
December 2024
CQC-IMS, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
Starch is one of the most abundant polysaccharides in nature and has a high potential for application in several fields, including effluent treatment as an adsorbent. Starch has a unique structure, with zones of different crystallinity and a glycosidic structure containing hydroxyl groups. This configuration allows a wide range of interactions with pollutants of different degrees of hydrophilicity, which includes from hydrogen bonding to hydrophobic interactions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!