The aim of this study is to examine the efficacy and applicability of the maximal opposition approach to treatment of an Arabic-speaking child with a phonological disorder. A 4:2 year old Jordanian boy, born and raised in Kuwait, received phonological therapy using a maximal opposition approach with major-class distinctions, using a single-case experimental design. The child's speech production accuracy improved. Success with this one child suggests phonological contrast therapy-specifically a maximal opposition approach-could be used to treat other Arabic-speaking children who present with phonological disorders. More research is required before the most appropriate technique and treatment frequency for Arabic speaking children can be determined.
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http://dx.doi.org/10.1016/j.jcomdis.2019.105913 | DOI Listing |
Curr Issues Mol Biol
November 2024
Faculty of Health Sciences, Universidad San Jorge, Autov. A-23 Zaragoza-Huesca Km. 299, 50830 Villanueva de Gállego, Zaragoza, Spain.
Exercise, despite being a beneficial activity for health, can also be a source of oxidative imbalance, which can lead to a decrease in performance. Furthermore, melatonin is an endogenous molecule that may counteract exercise-induced oxidative stress. The aim of this study was to evaluate the potential ergogenic and antioxidant capacity of melatonin administered for a maximal effort test.
View Article and Find Full Text PDFPLOS Glob Public Health
December 2024
Yale Law School, Yale School of Medicine, Yale Collaboration for Regulatory Rigor, Integrity, and Transparency, New Haven, Connecticut, United States of America.
Debates over the scope, terms, and governance of technology transfer-the sharing of essential technical information, know-how, and materials needed to manufacture a health product-are prominent and controversial in international health diplomacy. These debates have become focal points in recent contentious negotiations to amend the International Health Regulations (IHR) and draft a global Pandemic Agreement. While some countries advocate for automatic or compulsory mechanisms to facilitate access to health technologies, especially in times of crisis, others oppose legal frameworks that mandate non-voluntary participation by the pharmaceutical industry.
View Article and Find Full Text PDFBMC Neurol
October 2024
Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Background: SELENON-related myopathy (SELENON-RM) is a rare congenital myopathy characterized by slowly progressive axial muscle weakness, rigidity of the spine, scoliosis, and respiratory insufficiency. Laminin-a2-related muscular dystrophy (LAMA2-MD) has a similar clinical phenotype, which ranges from severe, early-onset congenital muscular dystrophy type 1A (MDC1A) to milder forms presenting as childhood- or adult-onset limb-girdle type muscular dystrophy. The first 1.
View Article and Find Full Text PDFInt J Numer Method Biomed Eng
October 2024
Department of Radiology, GuiQian International General Hospital, Guiyang, China.
Tumor treating fields (TTFields) is a novel therapeutic approach for the treatment of glioblastoma. The electric field intensity is a critical factor in the therapeutic efficacy of TTFields, as stronger electric field can more effectively impede the proliferation and survival of tumor cells. In this study, we aimed to improve the therapeutic effectiveness of TTFields by optimizing the position of electrode arrays, resulting in an increased electric field intensity at the tumor.
View Article and Find Full Text PDFBr J Soc Psychol
January 2025
The University of Queensland, Brisbane, Queensland, Australia.
Opposing social movements are groups that have conflicting objectives on a shared social justice issue. To maximize the probability of their movement's success, groups can strategically portray their group in a favourable manner while discrediting their opposition. One such approach involves the construction of victimization discourses.
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