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| http://dx.doi.org/10.3389/fmicb.2019.01324 | DOI Listing |
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High-level production of free fatty acids from lignocellulose hydrolysate by co-utilizing glucose and xylose in yeast.
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Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, 116023, PR China.
Lignocellulose bio-refinery via microbial cell factories for chemical production represents a renewable and sustainable route in response to resource starvation and environmental concerns. However, the challenges associated with the co-utilization of xylose and glucose often hinders the efficiency of lignocellulose bioconversion. Here, we engineered yeast to effectively produce free fatty acids from lignocellulose.
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Division of Public Health, Infectious Disease, and Occupational Medicine, Mayo Clinic, Rochester, MN, USA.
is a facultatively intracellular, gram-negative bacillus and a rare cause of infection in the United States. We report a case of a 45-year-old male who presented with ongoing fever, shortness of breath, and was found to have a pericardial effusion and pulmonic infiltrates due to . Though tularemia is classically associated with rabbits and rodents, we note the patient in our case had no clear infectious exposure.
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Universidade Católica Portuguesa, CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Rua Diego Botelho 1327, 4169-005 Porto, Portugal.
Food safety is a global concern driven by the constant need to find innovative solutions to mitigate contamination risks by pathogenic microorganisms [...
View Article and Find Full Text PDFFundamentals of bio-based technologies for selective metal recovery from bio-leachates and liquid waste streams.
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Department of Agrobiotechnology, IFA-Tulln, Institute of Environmental Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Tulln an der Donau, Austria.
The number of metal-containing waste streams resulting from electronic end-of life products, metallurgical by-products, and mine tailings to name but a few, is increasing worldwide. In recent decades, the potential to exploit these waste streams as valuable secondary resources to meet the high demand of critical and economically important raw materials has become more prominent. In this review, fundamental principles of bio-based metal recovery technologies are discussed focusing on microbial metabolism-dependent and metabolism-independent mechanisms as sustainable alternatives to conventional chemical metal recovery methods.
View Article and Find Full Text PDFMycophenolate mofetil: an update on its mechanism of action and effect on lymphoid tissue.
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Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Mycophenolate mofetil (MMF) is an immunosuppressive drug administered in the management of both autoimmune diseases and organ transplantation. The main aims of the study were: (a) to obtain information regarding the safety of using MMF in respect of its effect on normal T and B cells in lymphoid tissues; (b) to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF.
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