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Objectives: This study aimed to develop a prediction model for the detection of early sepsis-associated acute kidney injury (SA-AKI), which is defined as AKI diagnosed within 48 hours of a sepsis diagnosis.
Design: A retrospective study design was employed. It is not linked to a clinical trial.
On QSPR analysis of glaucoma drugs using machine learning with XGBoost and regression models.
Comput Biol Med
January 2025
Department of Mathematics and Statistics, The University of Lahore, Lahore Campus, Pakistan. Electronic address:
Glaucoma is an irreversible, progressive, degenerative eye disorder arising because of increased intraocular pressure, resulting in eventual vision loss if untreated. The QSPR relates, mathematically, by employing various algorithms, a specified property of a molecule that arises either from physical, chemical, or biological phenomena using various aspects of its structure. Here in, a similar application based on topological indices and inferences derived from the structure for the calculation of different drug properties like molar refractivity, refractive index, enthalpy, boiling points, molecular weight, and polarizability is presented.
View Article and Find Full Text PDFFirst trimester cervical angles for the prediction of spontaneous preterm birth.
Eur J Obstet Gynecol Reprod Biol
January 2025
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address:
Objective: First trimester cervical angles for the prediction of spontaneous preterm birth (sPTB) remains unclear. The objective is to explore the potential value of first trimester cervical angles for the prediction of sPTB.
Study Design: This was a secondary analysis of data derived from a prospective cohort study for sPTB screening in singleton pregnancies at 11 + 0-13 + 6 weeks in women attending routine Down's syndrome screening at Prince of Wales Hospital, Hong Kong SAR, between June 2018 and July 2020.
Racial and Ethnic Disparities in Pediatric Counseling on Nutrition, Lifestyle, and Weight: A Secondary Analysis of the BP-CATCH Randomized Clinical Trial.
JAMA Netw Open
January 2025
Department of Pediatrics, The Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York.
Importance: Pediatric obesity and hypertension are highly correlated. To mitigate both conditions, provision of counseling on nutrition, lifestyle, and weight to children with high blood pressure (BP) measurements is recommended.
Objective: To examine racial and ethnic disparities in receipt of nutrition, lifestyle, and weight counseling among patients with high BP at pediatric primary care visits stratified by patients' weight status.
Probiotic-based adsorbent mitigates aflatoxin B1 toxicity in Piaractus mesopotamicus: assessing well-being via changes in tissue architecture and digestive enzyme activity.
Vet Res Commun
January 2025
Faculdade de Ciências Agrárias, Universidade Federal da Grande Dourados, Rodovia Dourados - Itahum, km 12, Cidade Universitária, Dourados, MS, Brasil.
Aflatoxin is a mycotoxin produced by fungi of the genus Aspergillus that is present in various foods. Probiotics are well-established products in aquaculture, and due to their effective contribution to the intestine, they can be used as an aflatoxin adsorbent. This study evaluated the effects of aflatoxin B1 (AFB1) on enzymatic activity and intestinal function in Piaractus mesopotamicus (pacu) fingerlings fed diets containing a probiotic-based adsorbent (PBA).
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