FDG PET/CT of Gardnerella vaginalis Infection.

Clin Nucl Med

From the Nuclear Medicine Department.

Published: August 2019

AI Article Synopsis

  • A 23-year-old woman with cystic fibrosis and a lung transplant presented with swollen cervical lymph nodes and overall health decline, raising suspicion for lymphoma.
  • F-FDG PET/CT imaging revealed hypermetabolic lymph nodes in the cervical and pelvic regions but a biopsy showed no evidence of lymphoma.
  • Further testing indicated a positive result for Gardnerella vaginalis, highlighting that hypermetabolism in lymph nodes can occur in immunocompromised patients without indicating lymphoma.

Article Abstract

We report the case of a 23-year-old woman with a history of cystic fibrosis and bilung transplantation, who presented clinically cervical swollen lymph nodes with alteration of her general state. F-FDG PET/CT was performed because of lymphoma suspicion and showed cervical and pelvic hypermetabolic lymphadenopathies, with linear vaginal hypermetabolism. There was an increase of lactate dehydrogenase, and Epstein-Barr virus detection was negative. A right cervical lymph node biopsy was performed, with no lymphoma involvement. Complementary microbiological investigations showed positive results for Gardnerella vaginalis. F-FDG PET/CT lymphatic node hypermetabolism is not specific to lymphoma, particularly in immunocompromised patients.

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http://dx.doi.org/10.1097/RLU.0000000000002623DOI Listing

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