We report that fluoroquinolone-resistant Escherichia coli are found in feces of 8.8% of healthy women, with most bacteria belonging to pandemic multidrug-resistant ST131-H30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented urinary tract infection.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931843 | PMC |
| http://dx.doi.org/10.1093/cid/ciz547 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Trends in Bacterial Distribution and Antimicrobial Resistance in Intensive Care Units of Hubei Province, China: A Four-year Surveillance Study (2020-2023).
Curr Med Sci
December 2024
Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Objective: To investigate the distribution characteristics of common bacteria and changes in antimicrobial resistance in intensive care unit (ICU) patients in 58 hospitals in Hubei Province from 2020-2023.
Method: The antimicrobial agents for antimicrobial susceptibility tests was selected based on the 2022 China Antimicrobial Resistance surveillance system (CARSS) technical scheme, and the specific experimental operation was based on the requirements of the CLSI M02 and M07 documents. The commercial instruments were used following the manufacturer's instructions.
Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81.
Sci Rep
November 2024
Faculty of Medicine of Tunis - LR99ES09 Research Laboratory «Antimicrobial resistance», University of Tunis El Manar, 1007, Tunis, Tunisia.
Article Synopsis
- Fluoroquinolone-resistant (FQs-R) E. coli from patients undergoing prostate biopsies are increasingly common, raising concerns about using FQs for infection prevention.
- A study between 2016 and 2018 found that 61.06% of patients carried FQs-R Enterobacterales, primarily E. coli, with varying resistance profiles linked to specific genetic mutations.
- The research highlighted that these resistance mechanisms, including mutations in the gyrA and parC genes as well as certain plasmid-mediated resistance genes, significantly elevate the Minimum Inhibitory Concentrations (MICs), posing a risk for post-procedure infections.
Fluoroquinolone-resistant sequence type (ST)1193 is a profound, emerging lineage associated with systemic, urinary tract and neonatal infections. Humans, companion animals and the environment are reservoirs for ST1193, which has been disseminated globally. Following its detection in 2007, ST1193 has been identified repeatedly amongst fluoroquinolone-resistant clones in Australia.
View Article and Find Full Text PDFClonal and resistance profiles of fluoroquinolone-resistant uropathogenic in countries with different practices of antibiotic prescription.
Front Microbiol
October 2024
Department of Microbiology, University of Washington School of Medicine, Seattle, WA, United States.
Background: Antibiotic prescription practices differ between countries, influencing regional antimicrobial resistance prevalence. However, comparisons of clonal diversity among resistant bacteria in countries with different prescribing practices are rare. The rise of fluoroquinolone-resistant (FQREC), often multidrug-resistant, exacerbates global antibiotic resistance.
View Article and Find Full Text PDFHigh qnrS retention of ESBL-producing and mcr-harbouring colistin-resistant Escherichia coli in Vietnamese food products.
J Microorg Control
September 2024
Faculty of Contemporary Human Life Science, Tezukayama University.
Plasmid-mediated antibiotic-resistant bacteria's transmission is fatal and a major threat to public health. This study aimed to clarify the presence of plasmid-mediated quinolone resistance（PMQR）genes in extended-spectrum β-lactamase（ESBL）-producing or/and mcr-harbouring colistin（COL）-resistant Escherichia coli（ESBL-COL-EC）isolates from Vietnamese and Japanese chicken meat. Resistance towards ciprofloxacin（CIP）was examined in 308 ESBL-COL-EC isolates; CIP-resistant ESBL-COL-EC isolates were examined for the PMQR gene.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!