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Ultrathin ALD Coatings of Zr and V Oxides on Anodic TiO Nanotube Layers: Comparison of the Osteoblast Cell Growth.
ACS Appl Mater Interfaces
December 2024
Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00 Brno, Czech Republic.
The current study investigates and compares the biological effects of ultrathin conformal coatings of zirconium dioxide (ZrO) and vanadium pentoxide (VO) on osteoblastic MG-63 cells grown on TiO nanotube layers (TNTs). Coatings were achieved by the atomic layer deposition (ALD) technique. TNTs with average tube diameters of 15, 30, and 100 nm were fabricated on Ti substrates (via electrochemical anodization) and were used as primary substrates for the study.
View Article and Find Full Text PDFImpact of long-term trends on outcomes in the management of colonic diverticular bleeding: mediation analyses in a large multicenter study.
J Gastroenterol
December 2024
Department of Gastroenterological Endoscopy, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.
Background: Despite accumulating evidence and recommendations for management of colonic diverticular bleeding (CDB), the changes in its clinical management and outcomes remain unknown.
Methods: We performed a retrospective tendency analysis on a biennial basis, a propensity score-matched cohort study between the first and latter half groups, and mediation analyses to compare the diagnostic and treatment methods between January 2010 and December 2019 (CODE BLUE-J Study).
Results: A total of 6575 patients with CDB were included.
Oral intake of degalactosylated whey protein increases peripheral blood telomere length in young and aged mice.
Sci Rep
December 2024
Department of Endocrinology, Metabolism, and Hypertension Research, Clinical Research Institute, NHO Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto, 612-8555, Japan.
In order to elucidate novel actions of degalactosylated whey protein (D-WP) in comparison with intact whey protein (WP), the effects of oral intake of D-WP on peripheral blood telomere length and telomerase were examined in young and aged mice. In young mice, peripheral blood telomere length was significantly elongated following oral intake of D-WP for 4 weeks. mRNA expression of both telomerase reverse transcriptase (TERT) and telomerase RNA component (TERC) was significantly increased in the peripheral blood following oral intake of D-WP for 4 weeks.
View Article and Find Full Text PDFHeuristic-based vehicle arrangement for ro-ro ships.
Sci Rep
December 2024
Information Science and Engineering School, Northeastern University, Shenyang, 110819, Liaoning, China.
In this paper, a two-level search strategy fused with an improved no-fit polygon algorithm and improved bat algorithm is proposed to obtain the layout points of multiple vehicles. Additionally, a space-time scheduling strategy is proposed using the Improved D*Lite Algorithm (ID*Lite) and improved Bezier curve to generate the trajectories of individual vehicles. Furthermore, a conflict resolution strategy is introduced to address the collision conflict problem during multi-vehicle scheduling.
View Article and Find Full Text PDFThe optimal labelling method for artificial intelligence-assisted polyp detection in colonoscopy.
J Formos Med Assoc
December 2024
Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taiwan; Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan; Institute of Brain Science, National Yang Ming Chiao Tung University School of Medicine, Taiwan. Electronic address:
Background: The methodology in colon polyp labeling in establishing database for ma-chine learning is not well-described and standardized. We aimed to find out the best annotation method to generate the most accurate model in polyp detection.
Methods: 3542 colonoscopy polyp images were obtained from endoscopy database of a tertiary medical center.
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