AI Article Synopsis
- A case-series analysis evaluated the safety and effectiveness of combining pollen extract with vitamins to alleviate chronic inflammation in patients with class IV chronic prostatitis.
- Nineteen patients suspected of prostate cancer underwent biopsy, revealing class IV chronic prostatitis alongside high-grade prostatic intraepithelial neoplasia (HGPIN) or atypical small acinar proliferation (ASAP).
- After six months on the pollen extract and vitamins, 68.4% of patients showed reduced inflammation upon repeat biopsy, indicating potential therapeutic benefits.
Article Abstract
The aim of the present case-series analysis was to assess the safety and efficacy of pollen extract in association with vitamins in order to reduce the chronic prostatic inflammation in patients with class IV chronic prostatitis (CP). Nineteen non-consecutive patients performed a prostate biopsy for a suspect of prostate cancer. The biopsy histopathological examination showed a class IV CP, in presence of mild/moderate/high degree of inflammation, in association with an extensive (multiple biopsy sites, i.e., ≥ 3) high-grade prostatic intraepithelial neoplasia PIN (HGPIN) and/or atypical small acinar proliferation (ASAP). According to EAU Prostate Cancer Guidelines prostate biopsy was repeated after 6 months, because of the presence of extensive HGPIN or ASAP. Oral administration of pollen extract in association with vitamins (two capsules every 24 h) was prescribed until the repeat biopsy. Repeat biopsy histopathological examination showed, in 13 patients (68.4%), a lower degree of inflammation (absent/mild/moderate).
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| http://dx.doi.org/10.4081/aiua.2019.2.84 | DOI Listing |
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