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Mandibular anatomy of a new specimen of a prozostrodontian cynodont (Eucynodontia: Probainognathia) from the Upper Triassic of Brazil.
Naturwissenschaften
January 2025
Centro de Apoio à Pesquisa Paleontológica da Quarta Colônia Universidade Federal de Santa Maria (CAPPA/UFSM, Rua Maximiliano Vizzotto, 59897230-00, São João do Polêsine, Rio Grande do Sul, Brazil.
Prozostrodontia is a clade of probainognathian cynodonts that exhibit several morphological innovations later inherited by mammals. The earliest representatives of this group have been found in the Upper Triassic deposits of southern Brazil. In this study, we report the discovery of a probainognathian cynodont from the Buriol site (São João do Polêsine, Rio Grande do Sul, Brazil), Hyperodapedon Assemblage Zone (Late Triassic).
View Article and Find Full Text PDFTransthyretin-Related Familial Amyloidosis Polyneuropathy with Spinal Cord Damage: A Case Report.
Int Med Case Rep J
January 2025
Department of Neurology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang Cerebrovascular Disease (Stroke) Clinical Medical Research Center, Regional Medical Center for Neurological Diseases of Henan Province, Luoyang, People's Republic of China.
Introduction: Transthyretin protein-related familial amyloidosis polyneuropathy (TTR-FAP) is an autosomal dominant genetic disease caused by mutations in the TTR gene. The disease is characterized primarily by peripheral and autonomic nerve damage. Disease progression is associated with frequent involvement of the heart, lungs, kidneys, eyes, and other organs.
View Article and Find Full Text PDFRibosome customization and functional diversification among P-stalk proteins regulate late poxvirus protein synthesis.
Cell Rep
January 2025
Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:
Growing evidence suggests that ribosomes selectively regulate translation of specific mRNA subsets. Here, quantitative proteomics and cryoelectron microscopy demonstrate that poxvirus infection does not alter ribosomal subunit protein (RP) composition but skews 40S rotation states and displaces the 40S head domain. Genetic knockout screens employing metabolic assays and a dual-reporter virus further identified two RPs that selectively regulate non-canonical translation of late poxvirus mRNAs, which contain unusual 5' poly(A) leaders: receptor of activated C kinase 1 (RACK1) and RPLP2.
View Article and Find Full Text PDFUnusual presentation of a patient with partial anomalous pulmonary venous connections without a septal defect: a case report and literature review.
Int J Emerg Med
January 2025
Rajaie Cardiovascular Medical and Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Introduction: Partial anomalous pulmonary vein connections (PAPVC) are rare congenital abnormalities in which one or more pulmonary veins drain into the right atrium. This pathological condition may present in various ways, such as chest pain and dyspnea, or it may be diagnosed incidentally. Consequently, missed or late diagnoses are common, highlighting the importance of optimal diagnostic modalities.
View Article and Find Full Text PDFA giant specimen of and comments on the ontogeny of rhamphorhynchines.
PeerJ
January 2025
Rye, NY, United States of America.
is one of the best-known pterosaurs, with well over 100 specimens being held in public collections. Most of these represent juvenile animals, and the adults known are typically around 1 m in wingspan. Here we describe a near complete skeleton, preserved partially in 3D, of an animal with a wingspan of around 1.
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