Local and global measurements of parasite prevalence and abundance are critical for understanding the dynamics that underlie the diversity, distribution, and evolution of infectious diseases. Here, we present a data set of gut helminths found in (1) raccoons throughout their range, based on primary literature from 1925-2017 and (2) raccoons in Santa Barbara County, California, USA surveyed from 2012 to 2015. The range-wide data set has 1,256 parasite entries from 217 literature sources across three continents and 32 states in the USA. This data set includes a list of all recorded raccoon gut helminths (n = 100) and their presence and prevalence in surveyed raccoon populations. The Santa Barbara data set includes gut helminth data from 182 raccoons from one Southern California County. In addition to the presence and abundance data for 13 parasite species, this data set includes measurements of 7,465 individual raccoon roundworms (Baylisascaris procyonis). For both range-wide and Santa Barbara data sets, we include information on parasite site of infection in host, sampling method, and sample size. We also provide geographic coordinates for infected raccoon populations (range-wide database) and individuals (Santa Barbara). In the associated metadata, we include sampling methods and summary figures for both the range-wide and Santa Barbara raccoon gut helminth records. There are no copyright or proprietary restrictions for research and/or teaching purposes. S. B. Weinstein and J. C. Van Wert contributed equally to this manuscript and are shared first authors.
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http://dx.doi.org/10.1002/ecy.2807 | DOI Listing |
Circ Genom Precis Med
January 2025
Mary and Steve Wen Cardiovascular Division, Department of Medicine, University of California, Los Angeles. (W.F., N.D.W.).
Background: Lp(a; Lipoprotein[a]) is a predictor of atherosclerotic cardiovascular disease (ASCVD); however, there are few algorithms incorporating Lp(a), especially from real-world settings. We developed an electronic health record (EHR)-based risk prediction algorithm including Lp(a).
Methods: Utilizing a large EHR database, we categorized Lp(a) cut points at 25, 50, and 75 mg/dL and constructed 10-year ASCVD risk prediction models incorporating Lp(a), with external validation in a pooled cohort of 4 US prospective studies.
New Microbes New Infect
February 2025
Department of Veterinary Public Health and Epidemiology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, 125004, India.
Background: is a zoonotic tapeworm, commonly known as Asian It is an emerging sister species of with pigs as intermediate hosts. The present study aimed at genetic characterization and population structure analysis of metacestodes in slaughtered pigs in Haryana, north India.
Methods: In total, the vital organs of 253 slaughtered pigs were screened for the presence of metacestodes.
Front Neural Circuits
January 2025
Department of Advanced Medical and Surgical Sciences, Advanced MRI Research Center, University of Campania "Luigi Vanvitelli", Naples, Italy.
The substantia nigra pars compacta (SNc), one of the main dopaminergic nuclei of the brain, exerts a regulatory function on the basal ganglia circuitry via the nigro-striatal pathway but its possible dopaminergic innervation of the thalamus has been only investigated in non-human primates. The impossibility of tract-tracing studies in humans has boosted advanced MRI techniques and multi-shell high-angular resolution diffusion MRI (MS-HARDI) has promised to shed more light on the structural connectivity of subcortical structures. Here, we estimated the possible dopaminergic innervation of the human thalamus via an MS-HARDI tractography of the SNc in healthy human young adults.
View Article and Find Full Text PDFPredicting reaction barriers for arbitrary configurations based on only a limited set of density functional theory (DFT) calculations would render the design of catalysts or the simulation of reactions within complex materials highly efficient. We here propose Gaussian process regression (GPR) as a method of choice if DFT calculations are limited to hundreds or thousands of barrier calculations. For the case of hydrogen atom transfer in proteins, an important reaction in chemistry and biology, we obtain a mean absolute error of 3.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Background: Anterior cruciate ligament reconstruction (ACLR) is one of the most common orthopaedic procedures and one of the most well studied. Despite extensive research dedicated to ACLR, there is limited understanding of how chronic inflammatory systemic diseases (CIDs) such as rheumatoid arthritis and systemic lupus erythematosus affect outcomes.
Purpose: To compare the outcomes of ACLR in cohorts of patients with and without CID.
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