Background: Romanian laypeople's and health professionals' views on living organ donation were examined.
Methods: From July 2015 to May 2016, 263 adults (among them 31 physicians and 20 nurses) judged the acceptability of living organ donation in 42 realistic scenarios composed of varying levels of 6 factors: 1. type of organ, 2. whether it could have been obtained from a cadaver, 3. donor-recipient relationship, 4. donor's level of autonomy, 5. financial compensation, and 6. patients' level of responsibility for their illness. In all scenarios, the patients were in need of either a kidney or liver transplantation.
Results: The ratings were subjected to cluster analysis and analyses of variance. Seven qualitatively different positions were found that were termed never acceptable (12%), free market (44%), compensation (12%), altruism (6%), always acceptable (16%), responsibility (4%), and undetermined (6%). Physicians were more frequently in the free market or in the compensation clusters (81%) than laypeople (51%).
Conclusion: Only a few participants held the altruism model, even though this model has been promoted as the normative model by the World Health Organization and by most national legislations, including the legislation in Romania. Instead, the free market position and its variant-the compensation position-can be considered the majority positions (66%) in Romania.
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http://dx.doi.org/10.1016/j.transproceed.2019.04.033 | DOI Listing |
BMC Infect Dis
December 2024
Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zürich, Zurich, 8097, Switzerland.
Introduction: The ability to detect pathogenic bacteria before the onsets of severe respiratory symptoms and to differentiate bacterial infection allows to improve patient-tailored treatment leading to a significant reduction in illness severity, comorbidity as well as antibiotic resistance. As such, this study refines the application of the non-invasive Secondary Electrospray Ionization-High Resolution Mass Spectrometry (SESI-HRMS) methodology for real-time and early detection of human respiratory bacterial pathogens in the respiratory tract of a mouse infection model.
Methods: A real-time analysis of changes in volatile metabolites excreted by mice undergoing a lung infection by Staphylococcus aureus or Streptococcus pneumoniae were evaluated using a SESI-HRMS instrument.
J Biotechnol
December 2024
Laboratory of Electrochemistry and Nanotechnology, Institute of Technology and Research (ITP), Aracaju, Sergipe, Brazil; Process Engineering Graduate Program (PEP), Tiradentes University, Aracaju, Sergipe, Brazil.
Efficiently managing agricultural waste while innovating to derive value-added products is a significant challenge in the 21 century. In recent decades, these by-products have been increasingly explored as alternative sources for materials such as biosilica. Biosilica is renowned for its high surface area, biocompatibility, chemical stability, and modifiable surface, which makes it suitable for various applications.
View Article and Find Full Text PDFEBioMedicine
December 2024
Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, PR China; Zhejiang Key Laboratory of Clinical in Vitro Diagnostic Techniques, Hangzhou, 310003, PR China; Institute of Laboratory Medicine, Zhejiang University, Hangzhou, 310003, PR China. Electronic address:
Background: While metagenomic next-generation sequencing (mNGS) has been acknowledged as a valuable diagnostic tool for infections, its clinical validity and impact on patient management when using fresh tissue samples remains uncertain.
Methods: We conducted a retrospective cross-sectional study involving patients who underwent tissue mNGS at a tertiary hospital in China from February 2021 to February 2024, aiming to assess its ability to detect plausible pathogens and its clinical validity and impact.
Findings: A total of 520 mNGS results from 508 patients were analysed, detecting plausible pathogens in 302 (58.
Am J Case Rep
December 2024
Department of General Medicine, Saga University Hospital, Saga, Japan.
BACKGROUND Appropriate management of patients who have fallen is crucial for reducing damage and mortality. We report the case of a patient who fell from a seated position, which caused traumatic liver injury, with gastrointestinal symptoms as the primary patient concern. CASE REPORT A woman in her 80s who was living independently fell from a seated position during the daytime.
View Article and Find Full Text PDFBiogerontology
December 2024
Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Mitochondrial DNA encodes essential components of the respiratory chain complexes, serving as the foundation of mitochondrial respiratory function. Mutations in mtDNA primarily impair energy metabolism, exerting far-reaching effects on cellular physiology, particularly in the context of aging. The intrinsic vulnerability of mtDNA is increasingly recognized as a key driver in the initiation of aging and the progression of its related diseases.
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