Fast compression experiments performed using dynamic diamond anvil cells (dDACs) employing piezoactuators offer the opportunity to study compression-rate dependent phenomena. In this paper, we describe an experimental setup which allows us to perform time-resolved x-ray diffraction during the fast compression of materials using improved dDACs. The combination of the high flux available using a 25.6 keV x-ray beam focused with a linear array of compound refractive lenses and the two fast GaAs LAMBDA detectors available at the Extreme Conditions Beamline (P02.2) at PETRA III enables the collection of x-ray diffraction patterns at an effective repetition rate of up to 4 kHz. Compression rates of up to 160 TPa/s have been achieved during the compression of gold in a 2.5 ms fast compression using improved dDAC configurations with more powerful piezoactuators. The application of this setup to low-Z compounds at lower compression rates is described, and the high temporal resolution of the setup is demonstrated. The possibility of applying finely tuned pressure profiles opens opportunities for future research, such as using oscillations of the piezoactuator to mimic propagation of seismic waves in the Earth.
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http://dx.doi.org/10.1063/1.5098993 | DOI Listing |
Eur Heart J Imaging Methods Pract
January 2025
A.I. Virtanen Institute, University of Eastern Finland, Neulaniementie 2, 70210 Kuopio, Finland.
Aims: The aim of this study was to develop an ultra-short echo time 3D magnetic resonance imaging (MRI) method for imaging subacute myocardial infarction (MI) quantitatively and in an accelerated way. Here, we present novel 3D T- and T -weighted Multi-Band SWeep Imaging with Fourier Transform and Compressed Sensing (MB-SWIFT-CS) imaging of subacute MI in mice hearts .
Methods And Results: Relaxation time-weighted and under-sampled 3D MB-SWIFT-CS MRI were tested with manganese chloride (MnCl) phantom and mice MI model.
Int J Biol Macromol
January 2025
"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41 A Gr. Ghica Voda Alley, 700487, Iasi, Romania. Electronic address:
Conductive hydrogels are an appealing class of "smart" materials with great application potential, as they combine the stimuli-responsiveness of hydrogels with the conductivity of magnetic fillers. However, fabricating multifunctional conductive hydrogels that simultaneously exhibit conductivity, self-healing, adhesiveness, and anti-freezing properties remains a significant challenge. To address this issue, we introduce here a freeze-thawing approach to develop versatile, multiresponsive composite cryogels able to preserve their features under low-temperature conditions.
View Article and Find Full Text PDFBiomaterials
January 2025
Prometheus Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, PB 813, 3000, Leuven, Belgium; Skeletal Biology and Engineering Research, KU Leuven, ON1 Herestraat 49, PB 813, 3000, Leuven, Belgium. Electronic address:
Self-assembled cartilaginous microtissues provide a promising means of repairing challenging skeletal defects and connective tissues. However, despite their considerable promise in tissue engineering, the mechanical response of these engineered microtissues is not well understood. Here we examine the mechanical and viscoelastic response of progenitor cell aggregates formed from human primary periosteal cells and the resulting cartilaginous microtissues under large deformations as might be encountered in vivo.
View Article and Find Full Text PDFMagn Reson Imaging
January 2025
Department of Radiology, University Hospital of Strasbourg, 1 Avenue Moliere, 67098 Strasbourg, France.
Purpose: Compressed Sensing (CS) is an emerging technique to accelerate MRI acquisitions. The aim of this study was to assess the reliability and accuracy of cartilage thickness measurements in the knee using a CS-enabled isotropic 3D Fast Spin-Echo (FSE) sequence on a 3-T MRI scanner.
Methods: Twenty-eight tibial condyle sections were collected from 14 adult patients who underwent total knee arthroplasty.
PLoS Comput Biol
January 2025
Department of Mechanical Engineering & Materials Science, Washington University, St. Louis, Missouri, United States of America.
Cell collectives, like other motile entities, generate and use forces to move forward. Here, we ask whether environmental configurations alter this proportional force-speed relationship, since aligned extracellular matrix fibers are known to cause directed migration. We show that aligned fibers serve as active conduits for spatial propagation of cellular mechanotransduction through matrix exoskeleton, leading to efficient directed collective cell migration.
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