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Reversible splenial lesion in new-onset refractory status epilepticus: A case report. | LitMetric

Reversible splenial lesion in new-onset refractory status epilepticus: A case report.

Clin Neurol Neurosurg

Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan. Electronic address:

Published: August 2019

AI Article Synopsis

Article Abstract

A 33-year-old man developed a generalized tonic-clonic seizure after a week of fever and fatigue. Diffusion weighted and fluid attenuated inversion recovery magnetic resonance imaging showed a hyperintense lesion in the splenium of the corpus callosum, and the lesion disappeared within a few days. The patient developed refractory status epilepticus despite treatment with multiple antiepileptic drugs. After concurrent administration of high-dose methylprednisolone, intravenous immunoglobulin, intravenous anesthetics and antiepileptic drugs, the patient achieved complete suppression of seizures. To the best of our knowledge, this is the first case of a new-onset refractory status epilepticus with a reversible splenial lesion.

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Source
http://dx.doi.org/10.1016/j.clineuro.2019.105392DOI Listing

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