Mucormycosis is a rare but potentially mortal opportunistic infection caused by Mucorales. We present a case of rhinoorbital mucormycosis in an 11-year old male with neuroblastoma successfully treated with aggressive surgical debridement and antifungal combination of liposomal amphotericin B and posaconazole. Our patient developed signs of paranasal sinus infection and culture of fine needle biopsy grew . Prompt treatment and drastic surgical resection led to complete clinical and radiological recovery without evidence of mucormycosis relapse.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582074 | PMC |
| http://dx.doi.org/10.1016/j.mmcr.2019.06.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Role of myeloid-derived suppressor and Th17/Treg cells in post-COVID-19 Rhino-Orbital mucormycosis cases.
Immunopharmacol Immunotoxicol
February 2025
College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Rhino-Orbital-Cerebral Mucormycosis (ROCM) cases increased sharply in India during the second COVID-19 wave. Due to uncontrolled hyperglycemia, prolonged steroid use, and high ferritin levels, the immune system was dysregulated throughout this surge. Our study examined post-COVID-19 ROCM patients' T regulatory cell (Treg), T helper 17 cell (Th17) and Myeloid derived suppressor cell (MDSC) levels before and after three months of treatment.
View Article and Find Full Text PDFGuillain-Barre Syndrome in a Post-COVID-19 Patient who had Rhino-Orbital Mucormycosis.
Neurol India
November 2024
Department of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Rhino-Orbital Mucormycosis Presenting As Orbital Apex Syndrome With Central Retinal Artery Occlusion: A Rare Phenomenon.
Cureus
November 2024
Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Rhino-orbital-cerebral mucormycosis (ROCM) is an opportunistic infection that has increased due to COVID-19 with the use of corticosteroids and diabetes being the most important predisposing factors. Orbital apex syndrome with central retinal artery occlusion secondary to mucormycosis is relatively rare. This case report highlights a case of a 62-year-old female with poorly controlled diabetes and a history of COVID-19 two weeks prior, who presented with acute right eye painful visual loss for three days associated with bulging of the right eye and drooping of the eyelid.
View Article and Find Full Text PDFSubacute onset rhino-orbital mucormycosis caused by Cunninghamella in a Chinese leukemia patient: A case report and literature review.
Eur J Ophthalmol
November 2024
Department of Ophthalmology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, P.R. China.
Article Synopsis
- - A case of rhino-orbital mucormycosis (ROM) caused by the rare and lethal fungus Cunninghamella was reported in a 50-year-old woman with acute leukemia in China, marking the first instance of this specific infection in the country.
- - After undergoing two chemotherapy cycles, the patient developed severe naso-ocular symptoms along with black necrosis on her eyelids, leading to the diagnosis of ROM through tissue biopsy and multidisciplinary consultation.
- - Even though Cunninghamella infections carry a high mortality rate, the patient's life was saved by adjusting antifungal treatment and timely surgery, highlighting the importance of early detection for better outcomes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!