The synoptic-scale meteorological conditions leading up to the 30 most extreme subdaily summer rain events for two regions of the United Kingdom (northwest and southeast) were examined for the period 1979-2013. Using a recently available, quality controlled, national hourly rain gauge data set, we were able to identify extreme 3-hr rainfall accumulations that may be indicative of flash flooding. Composites of the state of the atmosphere leading up to these dates were produced to investigate synoptic-scale processes, thus potentially allowing for them to be identified in coarse resolution reanalyses and in climate models. The results show that the two regions have different dominant synoptic-scale conditions leading to extreme 3-hr rainfall, which is thought to be related to the type of rainfall typically experienced in each region. In particular, positive anomalies in mean sea level pressure and the geopotential height at 200 hPa over the United Kingdom are associated with extreme rainfall in the northwest, where the position of the westerly jet is also important. For the southeast, no clear anomalous synoptic-scale conditions could be identified; however, localized moisture sources and unstable air masses were observed in association with extremes. These results indicate the importance of better understanding of both synoptic-scale and thermodynamic drivers of short-duration extreme rainfall, with potential implications in forecasting and flood warning, as well as for understanding the representation of key processes by regional climate models.
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http://dx.doi.org/10.1029/2018JD029664 | DOI Listing |
Semin Oncol Nurs
January 2025
Nursing Department, Cyprus University of Technology, Limassol, Cyprus.
Objectives: Cancer-related cachexia affects approximately 50% to 80% of cancer patients and contributes significantly to cancer-related mortality, accounting for 20% of deaths. This multifactorial syndrome is characterized by systemic inflammation, anorexia, and elevated energy expenditure, leading to severe weight loss and muscle wasting. Understanding the underlying mechanisms is critical for developing effective interventions.
View Article and Find Full Text PDFInt J Cardiol
January 2025
Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Padova, Italy. Electronic address:
T wave inversion (TWI) on the electrocardiogram (ECG) is a relatively common finding in athletes. It poses a diagnostic challenge, as it can indicate either a benign physiological pattern or an early sign of serious cardiac pathology. This expert opinion statement provides a comprehensive review of the current understanding of TWI in athletes, emphasizing the importance of its localization, associated clinical features, and demographic factors in guiding its interpretation and management.
View Article and Find Full Text PDFComp Biochem Physiol A Mol Integr Physiol
January 2025
Department of Aquaculture, National Pingtung University of Science and Technology, Pingtung 912, Taiwan. Electronic address:
This study presents a comprehensive examination of the physiological adaptations of white shrimp (Penaeus vannamei) to low-salinity conditions and evaluates the effects of supplementing dietary glucose on disease resistance. Compared to the control group, shrimp cultured at a salinity of 4 psu exhibit significantly elevated expression levels of adenosine 5'-monophosphate-activated protein kinase (AMPK) in the hepatopancreas, which leads to increased energy expenditure and a corresponding reduction in resistance to infection by Vibrio alginolyticus. The suppression of AMPK via dsAMPK treatment markedly enhances disease resistance.
View Article and Find Full Text PDFTop Antivir Med
December 2024
University of Minnesota, Minneapolis, USA.
People with HIV (PWH) are living longer and experiencing a greater burden of morbidity from non-AIDS-defining conditions. Chronically treated HIV disease is associated with ongoing systemic inflammation that contributes to the development of chronic conditions (eg, cardiovascular disease) and geriatric syndromes (eg, frailty). Apart from HIV disease, a progressive increase in systemic inflammation is a characteristic feature of biologic aging, a process described as "inflammaging.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Department of Urology A, Ibn Sina Hospital, University of Rabat, Morocco. Electronic address:
Introduction: Multilocular cystic nephroma is an uncommon condition with only few cases described in the literature, although its benign nature is well-recognized.
Case Presentation: We present a case of a 28-year-old male patient who presented with a right flank pain, imaging suspected a multicystic renal cell carcinoma. A radical nephrectomy was performed view the size of the cyst and the high tumor complexity, which histology confirmed the diagnosis of multilocular cystic nephroma.
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