Granular cell tumor (GCT) is a rare soft tissue neoplasm. At present, there is limited information available on the incidence, diagnosis, and treatment of GCTs. Therefore, we perform magnetic resonance imaging (MRI) of a perianal GCT case and review the literature of other reported cases to obtain a more comprehensive understanding of the disease. Here, we describe a rare case of perianal GCT in a 53-year-old female who presented with recurrent abdominal pain. Contrast-enhanced MRI demonstrated a well-defined perianal GCT mass, and the diagnosis was confirmed by immunostaining after mass excision. During a 10-month follow-up, there had been no evidence of recurrence. In addition, we discussed the findings of other perianal GCT cases, with regard to their age, gender, MRI analysis results, pathologic features, and treatment outcomes.
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http://dx.doi.org/10.1016/j.radcr.2019.05.010 | DOI Listing |
Clin Case Rep
December 2024
Division of Surgical Oncology, Department of Surgery Eastern Carolina Brody School of Medicine Greenville North Carolina USA.
Granular cell tumors (GCTs) are uncommon soft tissue neoplasms derived from Schwann cells that can arise from various regions of the body. The majority originate from the head and neck. They are rarely encountered in the gastrointestinal tract and even more rarely in the anorectal region.
View Article and Find Full Text PDFFront Oncol
September 2022
Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Granulosa cell tumor (GCT) is a rare tumor that originates from neural/Schwann cells. GCTs can occur at any age and at any site in the body. The most common site is the tongue, followed by the mammary gland, upper respiratory tract ( throat and bronchus), and gastrointestinal tract (esophagus, large intestine and perianal area, stomach, small intestine, and bile duct).
View Article and Find Full Text PDFJ Int Med Res
January 2021
Department of Oncology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Granular cell tumors (GCTs) are rare submucosal neoplasms, with tumors in the oral mucosa accounting for about a third of all cases. In contrast, GCT is a rare anal neoplasm, with fewer than 30 cases of perianal GCT reported in the literature. We report the case of a 36-year-old woman with a perianal lump with no obvious local lesion as the main clinical complaint.
View Article and Find Full Text PDFRadiol Case Rep
August 2019
Department of Radiology, Shuguang Hospital, Shanfghai University of Traditional Chinese Medicine, No. 528, Zhangheng Road, Pudong district, Shanghai, China.
Ann Gastroenterol
May 2018
Department of Internal Medicine, Division of Gastroenterology, Albany Medical Center, Albany, NY (Micheal Tadros), USA.
Granular cell tumors (GCTs) are generally thought to be of Schwann cell origin and are typically S-100 positive. Up to 11% of these tumors affect the gastrointestinal tract, most commonly the esophagus, colon, and stomach. While GCTs are mostly benign, malignant and metastatic GCTs have been reported.
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