A bioassay-guided phytochemical study of a leaf extract with antifungal activity permitted the identification of 28 compounds, including the new 6-(βboivinopyranosyl)apigenin (), 8-(βoliopyranosyl)apigenin (), ()-6-(2-carboxyethenyl)apigenin (), ()-8-(2-carboxyethenyl)apigenin (), and 7,5″-anhydro-6-(α-2,6-dideoxy-5-hydroxyarabinohexopyranosyl)apigenin (). The structures of the new compounds were determined by comprehensive spectroscopic analysis, including 1D and 2D NMR techniques, and by mass spectrometry. Compound showed promising activity and selectivity against (IC 44 nM), which exhibits resistance to azoles. The association of the major components 3-β-d-glucopyranosyloxysitosterol () and ethyl gallate () was synergistic against , especially the IC values of compound , which were reduced by more than 100-fold.
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