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Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring. | LitMetric

Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring.

Chem Commun (Camb)

Instituto de Química - Universidad Nacional Autónoma de México, Ciudad Universitaria, Circuito Exterior s/n, De. Coyoacán 04510, Ciudad de México, Mexico.

Published: July 2019

AI Article Synopsis

Article Abstract

A dual-emissive fluorescent probe enabling dynamic changes in nuclear local microviscosity monitoring was developed. The new sensing scenario involves probe subcellular localization redistribution, allowing a quantitative analysis of the local microviscosity related to nuclear damage in the presence of agents perturbing the nuclear morphology. With the aid of an organotin(iv) in situ formed complex we propose a different scenario of bioanalytical applications through confocal microscopy.

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Source
http://dx.doi.org/10.1039/c9cc04179fDOI Listing

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