AI Article Synopsis

  • Perineuritis is a rare condition affecting peripheral nerves, characterized by swelling and inflammation in the perineurium.
  • A 52-year-old man experienced pain, muscle weakness, and reduced sensation in his legs, prompting a sural nerve biopsy that confirmed perineuritis.
  • Treatment with oral prednisolone, plasma exchange, and intravenous immunoglobulin successfully improved his symptoms significantly.

Article Abstract

Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815884PMC
http://dx.doi.org/10.2169/internalmedicine.2638-19DOI Listing

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