How to say "no" most effectively: Evaluating resistance strategies for prescription stimulant diversion to inform preventive interventions.

We evaluated the perceived effectiveness of resistance strategies students could employ if approached to give away, trade, or sell their prescription stimulant medication, a growing concern on college campuses. We sampled undergraduates ( = 1,521) at three demographically dissimilar institutions between Fall 2017 and Spring 2018. We administered an anonymous, online survey and used linear mixed models to examine the effects of strategy type, face support (ie, adding politeness), and substance use history on perceived strategy effectiveness. Internal (eg, "I am not comfortable sharing my medication") and external (eg, "My doctor won't prescribe me if I share") explanations were perceived to be most effective. Excuses, direct refusals, and suggesting an alternative (eg, energy drink) were less preferred. Adding face support improved perceived effectiveness for direct refusals and internal explanations. Preventive interventions for stimulant diversion could encourage the use of internal or external explanations or direct refusals with face support.