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Visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones at the C3-position. | LitMetric

Visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones at the C3-position.

Org Biomol Chem

College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, P. R. China. and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.

Published: July 2019

AI Article Synopsis

Article Abstract

A simple and efficient method for the visible light induced direct carbon alkylation of quinoxalin-2(1H)-ones at the C3 position is described. This protocol employs cheap and readily available phenyliodine(iii) dicarboxylates as the alkylation reagents to conduct decarboxylative radical coupling reaction with quinoxalin-2(1H)-ones. The process exhibits excellent compatibility to functional groups and provides a convenient and selective access to various 3-alkylquinoxalin-2(1H)-ones in good yields.

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Source
http://dx.doi.org/10.1039/c9ob01169bDOI Listing

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