In this study, a novel near-infrared fluorescent off-on probe for HS based on seminaphthorhodafluor fluorophore is designed and constructed, which could be used in detection with 121-fold (23-fold) fluorescent (absorbance) enhancement at 630 nm (572 nm), fast responsiveness (completed within 5 min), high sensitivity, and lower cellular autofluorescence interference. Based on these excellent optical properties, the probe was employed to monitor HS in red wine samples with satisfactory results. Moreover, the probe was successfully applied for monitoring and imaging HS quantitatively in Hela cells and live athymic nude mice, indicating its potential application in biological science.
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| http://dx.doi.org/10.1007/s00216-019-01973-1 | DOI Listing |
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