Hemiplegia and focal convulsions as a manifestation of cyclosporine A toxicity.

J Clin Pharmacol

Bone Marrow Transplant Team, Westminster Children's Hospital, London SWI, United Kingdom.

Published: November 1987

Hemiplegia and focal convulsions were observed in a patient who received cyclosporine A after bone marrow transplantation. Cessation of the drug resulted in prompt reversal of the symptoms. The diagnostic problems and implications of this case are discussed.

Download full-text PDF

Source
http://dx.doi.org/10.1002/j.1552-4604.1987.tb05588.xDOI Listing

Publication Analysis

Top Keywords

hemiplegia focal
8
focal convulsions
8
convulsions manifestation
4
manifestation cyclosporine
4
cyclosporine toxicity
4
toxicity hemiplegia
4
convulsions observed
4
observed patient
4
patient received
4
received cyclosporine
4

Similar Publications

Transcranial neurosurgery assisted by endoscopy and intraoperative ultrasound (IOUS) has become an effective approach for real-time visualization and guidance during tumor resection. This study explores the application of these techniques in falcine meningioma (FM) resection, assessing their feasibility and safety. Eleven FM patients underwent transcranial endoscopic resection with IOUS assistance.

View Article and Find Full Text PDF

Objective: To investigate the frequency of epileptiform discharges associated with self-limited focal epilepsy (EDSelFEC) in children who have undergone a hemispherotomy and to evaluate whether patients with coexistence of EDSelFEC and structural hemispheric epilepsies differ from patients without coexistence of EDSelFEC and whether there are differences between the two groups with regard to preoperative management and postoperative outcome.

Methods: Data on 131 children who underwent a hemispherotomy between January 1999 and January 2015 were retrieved from the Epilepsy center's epilepsy surgery database. Children with EDSelFEC were compared with children without EDSelFEC with respect to epileptogenic hemispheric pathology, family history, age at epilepsy onset, timing of surgery, lesion laterality, preoperative cognitive function, response to sodium channel blocker antiepileptic medication, and surgical outcome.

View Article and Find Full Text PDF

Upper extremity function and disability recovery with vibration therapy after stroke: a systematic review and meta-analysis of RCTs.

J Neuroeng Rehabil

December 2024

National Center for Geriatrics and Welfare Research, National Health Research Institutes, No. 8, Xuefu W. Rd., Huwei Township, Yunlin County, 63247, Taiwan (R.O.C.).

Background: This study aimed to investigate the therapeutic effects of vibration therapy for improving upper extremity motor impairment, function, and disability recovery in people with stroke.

Design: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. PubMed, EMBASE, the Cochrane Library Database, Physiotherapy Evidence Database (PEDro), China Knowledge Resource Integrated Database, and Google Scholar were searched from inception to May 31, 2024.

View Article and Find Full Text PDF

Hemiplegic Cerebral Palsy (CP) is the most common pediatric motor disability, characterized by unilateral motor weakness. Pediatric Constraint-Induced Movement Therapy (pCIMT) improves affected extremity function but faces variable clinical integration. This study assessed U.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!