AI Article Synopsis
- The study investigates the safety and efficacy of per-oral endoscopic tumor resection (POET) for treating submucosal tumors (SMTs) in the esophagus and gastric cardia.
- POET was effective in 91.5% of cases with no major complications, but larger tumors (minor axis diameter >30 mm or tumor mass index >1000) may require surgical intervention.
- The findings suggest that while POET is a viable option for SMTs, careful consideration is needed for tumors with malignant potential to ensure the best outcomes.
Article Abstract
Objectives: The clinical success of per-oral endoscopic myotomy (POEM) has led to the development of a new field of 'submucosal endoscopy'. This study aimed to evaluate the safety, efficacy, and limitations of per-oral endoscopic tumor resection (POET) in the management of submucosal tumors (SMTs) in the esophagus and the gastric cardia.
Methods: POET was performed in 47 patients from January 2011 to December 2017. The indication for POET was SMTs ≤ 30 mm in minor axis diameter. Patient and tumor characteristics (age, gender, tumor location, size, and histology), operative and clinical results of POET (procedure time and completion rate, en bloc resection rate, length of hospitalization, adverse events and tumor recurrence) were analyzed retrospectively.
Results: POET was successfully completed in 43 patients (91.5%) without any major adverse events (Clavien-Dindo IIIb-IV). Four patients required conversion to an open surgical procedure due to suboptimal visualization during POET. Four patients underwent piecemeal resection of their SMTs including GISTs. Median follow-up was 44 months (10-96 months), during that time, there were no incidences of tumor recurrence. Tumors that had a minor axis diameter > 30 mm or a tumor mass index (TMI) [major axis diameter (mm) × minor axis diameter (mm)] >1000 had a high likelihood of being converted to surgical resection.
Conclusions: POET is a safe and effective treatment for SMTs. However, in patients where the minor axis diameter is > 30 mm or the TMI > 1000, surgical excision should be considered. Furthermore, application of POET for SMTs with malignant potential should be carefully considered to ensure optimal oncologic outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/den.13471 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders.
Poult Sci
January 2025
College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China. Electronic address:
To investigate the regulatory mechanism mediated by hypothalamic OPN5 on seasonal changes in the reproductive activities of domestic geese, 60 Magang ganders in their breeding period were selected for the experiment and evenly divided into an immunization group(OPN5-IM) and a control group. On days 0, 15 and 30, ganders in the immunized group were immunized with OPN5-KLH protein vaccine, and ganders in the control were immunized with the same amount of blank emulsified vaccine. Additionally, 120 female geese were provided to stimulate the reproductive activities of male geese.
View Article and Find Full Text PDFMolecular mechanisms of libido influencing semen quality in geese through the hypothalamic-pituitary-testicular-external genitalia axis.
Poult Sci
December 2024
Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, PR China; State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, PR China. Electronic address:
Libido plays a crucial role in influencing semen quality, yet the underlying regulatory mechanisms remain unclear. As a central axis in male goose reproduction, the hypothalamic-pituitary-testicular-external genitalia (HPTE) axis may contribute to the regulation of this process. In this study, we established a rating scale for goose libido based on average number of massages to erection (ANM) and the erection type, and evaluated semen quality across the entire flock.
View Article and Find Full Text PDFSuperficial palmar branch of radial artery flap for digital skin reconstruction: anatomical study and clinical applications.
Surg Radiol Anat
December 2024
Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Article Synopsis
- The study examines the superficial palmar branch of the radial artery (SUPBRA) to improve techniques for reconstructing palmar skin, focusing on its anatomy and harvesting methods.
- Researchers dissected 19 male hand specimens to gather detailed anatomical data, including dimensions and positions of key structures related to SUPBRA, analyzing how best to utilize this flap in reconstruction efforts.
- Results indicated that the SUPBRA has adequate dimensions for viability in surgical applications, with specific measurements and the identification of critical vascular contributions that ensure successful use in cases of hand injury.
Effects of capsulorhexis size and position on post-surgical IOL alignment.
Sci Rep
December 2024
Visual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
In cataract surgery, post-surgical stability of the intraocular lens plays a major role. This study aims to explore how the size and decentration of the capsulorhexis affect intraocular lens decentration and tilt by using numerical methods. Finite element models included zonules, ciliary body, capsular bag, and an IOL with two open-loop haptics were built.
View Article and Find Full Text PDFResidual dentin thickness and biomechanical performance of post-and-core-restored mandibular premolars: A finite element analysis study.
J Prosthet Dent
December 2024
Associate Chief Physician, Department of Prosthodontic, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, PR China. Electronic address:
Statement Of Problem: Endodontically treated teeth often require post-and-core restorations for structural support because of extensive hard tissue loss. Assessment of the effect of the residual dentin thickness on the biomechanical performance of these restorations is lacking.
Purpose: The purpose of this study was to evaluate the residual dentin thickness in mandibular premolars after post-and-core restorations using cone beam computed tomography (CBCT) and to analyze the stress distribution with finite element analysis (FEA).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!