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Hydroxychloroquine-induced Sweet's Syndrome: A Case Report and Literature Review.
Acta Derm Venereol
January 2025
Dermatology Department, Unidade Local de Saúde Santa Maria, Lisbon, Portugal; Dermatology University Clinic, Faculty of Medicine, University of Lisbon, Lisbon, Portugal; Dermatology Research Unit, Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal.
Sweet's syndrome (or acute febrile dermatosis) is a neutrophilic dermatosis with a characteristic presentation encompassing specific clinical (fever and erythemato-violaceous oedematous papules, plaques and nodules), laboratory (neutrophilia and increased inflammatory markers), and histological (dermal neutrophilic infiltrate without vasculitis) features. Its pathophysiology is poorly understood but there seems to be an auto-inflammatory component related to mutations in inflammasome genes. It has been subdivided into its classic form, malignancy-associated, and drug-induced, according to its aetiology.
View Article and Find Full Text PDFPrimary cutaneous CD4 small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co ablation: a case report and literature review.
Dermatol Reports
November 2024
Department of Medical Sciences and Surgery, University of Bologna.
This case report describes an 83-year-old patient with a history of non-melanoma skin cancer who presented with a violaceous, painless nodule on the neck. Dermoscopic examination and subsequent biopsy revealed a Small/Medium CD4 T-cell lymphoproliferative disorder (SMPLPD) of the skin. Although excision was initially recommended, the patient opted for treatment with CO laser ablation.
View Article and Find Full Text PDF[Clinical, demographic and histopathological characteristics of individuals with Kaposi's sarcoma and living with HIV in Mexico].
Rev Med Inst Mex Seguro Soc
November 2024
Secretaría de Salud, Hospital General de México "Dr. Eduardo Liceaga", Servicio de Dermatología Dr. Mario Magaña Lozano. Ciudad de México, México.
Article Synopsis
- KS is the most common cancer among HIV-positive individuals in developing countries, significantly impacting their quality of life.
- The study included 28 male HIV-positive patients diagnosed with KS, revealing that most had low CD4+ counts, high viral loads, and common skin lesions associated with the disease.
- Antiretroviral therapy demonstrated a long-term protective effect against KS, but opportunistic infections, particularly tuberculosis, were prevalent, emphasizing the need for a comprehensive approach in managing both KS and related infections.
Fegeler Syndrome Mimicking Kaposi Sarcoma: A Case Report.
Cureus
October 2024
Pathology, Hacettepe University, Ankara, TUR.
Acquired capillary malformation, also known as Fegeler syndrome, is a rare condition in adults, often linked to trauma. This report presents a 49-year-old male with a violaceous nodule on the fourth toe, clinically resembling Kaposi's sarcoma. Dermoscopic examination revealed surface scaling, thick intersecting white lines, and a rainbow pattern.
View Article and Find Full Text PDFTender violaceous nodules and petechia on the legs.
JAAD Case Rep
November 2024
Department of Dermatology, Tufts Medical Center, Boston, Massachusetts.
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