Although Mohs micrographic surgery (MMS) is the gold standard for treatment of nonmelanoma skin cancers (NMSCs), laser management has been an emerging treatment option that continues to be studied. Nonablative laser therapy is a noninvasive alternative. This study used a combined pulsed dye laser (PDL) and fractional laser approach to treat basal cell carcinomas (BCCs) in conjunction with noninvasive imaging such as reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) to enhance efficacy rates.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Development of an ex vivo model to assess the impact of fumonisin B on swine intestinal morphology.
Toxicon
January 2025
Federal University of Santa Maria, Laboratory of Mycotoxicological Analyses, Santa Maria, Rio Grande do Sul, Brazil. Electronic address:
This study was conducted to assess the effects of fumonisin B (FB) on the jejunum of pigs using a novel ex vivo model conducted in parallel with an in vivo trial. For the in vivo model, twelve male 28 to 70-days-old pigs were subjected to two treatments of six animals each: the control group, fed a basal diet (BD), and the FB group, fed the BD + 50 mg/kg FB. At 70 days, the animals were slaughtered and one jejunal sample was collected from each pig for further histopathological analyses.
View Article and Find Full Text PDFPhase I trial of phIL12 plasmid intratumoral gene electrotransfer in patients with basal cell carcinoma in head and neck region.
Eur J Surg Oncol
January 2025
Institute of Oncology Ljubljana, Slovenia; Faculty of Health Sciences, University of Ljubljana, Slovenia. Electronic address:
Introduction: In the treatment of cancer, immunomodulatory approaches are developed to support the organism in fighting cancer or to enhance the immunomodulatory effects of local ablative techniques. To this end, we conducted an interventional, open-label, single-arm Phase I trial to evaluate the safety and tolerability of intratumoral phIL12 plasmid DNA gene electrotransfer as primary objectives.
Methods: The study was dose-escalating with 3 consecutive cohorts of 3 patients per phIL12 dose level (0.
An efficient electrocatalytic in-situ hydrogen peroxide generation for ballast water treatment with oxygen groups.
Sci Total Environ
January 2025
Ability R&D Energy Research Centre, School of Energy and Environment, City University of Hong Kong, Hong Kong; State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong.
The in-situ electrochemical production of hydrogen peroxide (HO) offers a promising approach for ballast water treatment. However, further advancements are required to develop electrocatalysts capable of achieving efficient HO generation in seawater environments. Herein, we synthesized two-dimensional lamellated porous carbon nanosheets enriched with oxygen functional groups, which exhibited exceptional performance in HO electrosynthesis.
View Article and Find Full Text PDFMolecular evidence for the efficacy of PBM therapy in the treatment of Oral lichen planus.
Photodiagnosis Photodyn Ther
January 2025
Department of Healthcare and Social Work, New Bulgarian University, Sofia, Bulgaria. Electronic address:
Purpose: Oral lichen planus (OLP) is a chronic inflammatory disease, in which T-Lymphocytes induce apoptosis of basal keratinocytes, leading to the formation of symptomatic lesions. It is assumed that blocking the cell death program and enhancing cell proliferation would be crucial to the healing process. The aim of the study was to verify the efficacy of Photobiomodulation (PBM) in OLP management, by evaluating the effects of laser irradiation on the processes of apoptosis and cell proliferation.
View Article and Find Full Text PDFThe maize mTERF18 regulates transcriptional termination of the mitochondrial nad6 gene and is essential for kernel development.
J Genet Genomics
January 2025
National Engineering Laboratory of Crop Stress Resistance, College of Life Science, Anhui Agricultural University, Hefei, Anhui 230036, China. Electronic address:
Mitochondria are semi-autonomous organelle present in eukaryotic cells, containing their own genome and transcriptional machinery. However, their functions are intricately linked to proteins encoded by the nuclear genome. Mitochondrial transcription termination factors (mTERFs) are nucleic acid-binding proteins involved in RNA splicing and transcription termination within plant mitochondria and chloroplasts.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!