Cytotoxic -terphenyls from the deep-sea-derived .

Nat Prod Res

Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, China.

Published: May 2021

From the deep-sea-derived fungus , one novel () and three known (-) -terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for anti-food allergic and antitumor bioactivities. Compounds and showed potent antiproliferative effect against four cancer cells of Hela, Eca-109, Bel-7402, and PANC-1 with IC values ranging from 5.5 M to 9.4 M.

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Source
http://dx.doi.org/10.1080/14786419.2019.1633651DOI Listing

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