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Use of Tranexamic Acid in SARS-COV-2: Boon or Bane?
Arch Razi Inst
June 2024
Department of Community and Family Medicine, AIIMS Bibinagar, Hyderabad, Telangana-508126.
The devastating pandemic of SARS-CoV-2 (COVID-19) began in Wuhan, China, and spread rapidly through most parts of the world in the second half of 2020. The air droplet spread of SARS-CoV-2 is of great global health concern as it is potentially fatal. Various drugs and treatment modalities have been tried to date, but none have been found to be definitive.
View Article and Find Full Text PDFLucio's phenomenon in a non-endemic region: A case report.
SAGE Open Med Case Rep
December 2024
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Leprosy remains a persistent health challenge in endemic regions with cases rising in non-endemic regions such as North America. Patients with leprosy present with a variety of symptoms including limited skin lesions in tuberculoid leprosy to extensive lesions and high bacterial proliferation in lepromatous leprosy. This case report details a 77-year-old Canadian man of South Asian descent with lepromatous leprosy and Lucio's phenomenon in Western Canada.
View Article and Find Full Text PDFPrevalence, pattern, contact sensitisers and impact on quality-of-life of occupational dermatitis among beekeepers in North India.
Contact Dermatitis
November 2024
Department of Dermatology, Venereology and Leprosy, Government Medical College Srinagar, University of Kashmir, Srinagar, Jammu and Kashmir, India.
Article Synopsis
- * Conducted over 18 months, the study involving 340 beekeepers found a 17.1% prevalence of dermatitis, primarily affecting hands, with significant links to how long individuals have been beekeeping and prior allergy history.
- * Although dermatitis is common among beekeepers, the overall effect on their quality of life is relatively minor, with propolis identified as a key allergen in the region.
Low completion rate for the 6-months course of isoniazid preventive therapy among people living with HIV, North Eastern Uganda, 2015-2017.
Pan Afr Med J
November 2024
Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda.
Introduction: isoniazid preventive therapy (IPT) is highly effective at preventing tuberculosis among Persons Living with HIV (PLHIV). However, IPT completion rates in Uganda have not been studied. We examined completion rates for the 6-month course of IPT and factors associated with non-completion among PLHIV in northeastern Uganda.
View Article and Find Full Text PDFPrevalence of rifampicin and isoniazid mono-resistance among cases of pulmonary tuberculosis from Western Uttar Pradesh, North India.
Mol Biol Rep
October 2024
Department of Microbiology and Molecular Biology, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Taj Ganj, Agra, 282 001, India.
Article Synopsis
- - The study investigates the prevalence of mono-resistance to rifampicin and isoniazid in tuberculosis (TB) patients in Western Uttar Pradesh, finding that 19.51% were multi-drug resistant while 8.54% and 6.10% were mono-resistant to rifampicin and isoniazid, respectively.
- - Out of 153 sputum samples processed, 54.24% tested positive for Mycobacterium tuberculosis, with the majority being identified through specific culture and testing methods.
- - Findings indicate a higher occurrence of mono-resistance in male patients over 45, those living in rural areas, experiencing weight loss, or with previous TB treatment; the study calls for better monitoring
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