BACKGROUND The effective and safe treatment of chronic frequently relapsing pancreatitis is challenging. CASE REPORT We present the case of a 63-year-old male patient with severe complications of this variant of the disease: parapancreatitis with the formation of an inflammatory mass, fermentative ascites-peritonitis, 2-sided pleural effusions, sepsis, and cachexia. Conservative treatment was ineffective, and emergency surgery was chosen. A novel surgical procedure - open internal stenting of the main pancreatic duct via pancreatowirsungotomy and duodenotomy - was used successfully in this difficult case. The elimination of pancreatic ductal hypertension and maintenance of maximum physiological pancreatic juice outflow, achieved via surgery, led to rapid improvement in the patient's condition. He was discharged on the 26th day after surgery. The clinical outcome was good at the 2-year follow-up. CONCLUSIONS Open stenting of the main pancreatic duct can be recommended for treating patients similar to the patient described in this paper - having severe complications of CP against the background of a relapse, exhaustion, and being in a severely or critically ill general condition. This surgical procedure is especially important when minimally invasive methods of eliminating pancreatic hypertension are technically unsuccessful or impossible due to the lack of necessary equipment and staff.
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http://dx.doi.org/10.12659/AJCR.916587 | DOI Listing |
J Mol Cell Cardiol
December 2024
A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland; Heart Centre and Gene Therapy Unit, Kuopio University Hospital, Kuopio, Finland. Electronic address:
Background: Coronary stenting operations have become the main option for the treatment of coronary heart disease. Vessel recovery after stenting has emerged as a critical factor in reducing possible complications. In this study, we evaluated the feasibility, safety and efficacy of locally administered intraluminal gene therapy delivered using a specialized infusion balloon catheter.
View Article and Find Full Text PDFProg Cardiovasc Dis
December 2024
University of Virginia, Division of Cardiovascular Medicine, Department of Medicine, Charlottesville, VA 22901, United States of America. Electronic address:
Revascularization has been demonstrated to be clearly superior to medical therapy for significant unprotected left main coronary artery (LMCA) disease. Coronary artery bypass graft surgery (CABG) has a class 1 indication in both the American and European society guidelines for the treatment of LMCA disease. However, for the population of patients who are declined CABG after a heart team evaluation, percutaneous coronary interventional (PCI) may be an efficacious alternative.
View Article and Find Full Text PDFRev Cardiovasc Med
December 2024
Department of Cardiology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Background: Elective unprotected left main (ULM) percutaneous coronary intervention (PCI) has long-term mortality rates comparable to surgical revascularization, thanks to advances in drug-eluting stent (DES) design, improved PCI techniques, and frequent use of intravascular imaging. However, urgent PCI of ULM culprit lesions remains associated with high in-hospital mortality and unfavourable long-term outcomes, including DES restenosis and stent thrombosis (ST). This analysis aimed to examine the long-term outcomes and healing of DES implanted in ULM during primary PCI using high-resolution optical coherence tomography (OCT) imaging.
View Article and Find Full Text PDFAnticancer Res
January 2025
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Background/aim: To investigate risk factors of late acute remnant pancreatitis after pancreatoduodenectomy (PD), we propose the use of a suturing pitch calculated based on the diameter of the main pancreatic duct and the number of sutures used in the pancreatic duct-to-mucosa anastomosis. This study aimed to determine whether the suturing pitch can predict late acute pancreatitis following PD.
Patients And Methods: This study included 142 patients who underwent elective PD.
Int Urol Nephrol
December 2024
Department of Urology, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cui Ying, Lanzhou, 730030, Gansu Province, China.
Objective: To analyze and discuss the clinical characteristics and risk factors of bilateral renal tuberculosis.
Methods: A retrospective study was performed on 446 patients who were diagnosed with renal TB. Among these patients, 69 patients with bilateral renal TB were selected as the observation group, and 377 patients with unilateral renal TB served as the control group.
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