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Harnessing Corneal Stromal Regeneration for Vision Restoration: A Comprehensive Review of the Emerging Treatment Techniques for Keratoconus.
Cureus
September 2024
Ophthalmology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Keratoconus is a progressive corneal disorder characterized by thinning and conical protrusion, leading to visual impairment that often necessitates advanced treatment strategies. Traditional management options, including corrective lenses, corneal cross-linking (CXL), and surgical interventions such as corneal transplants and intracorneal ring segments (ICRS), address symptoms but have limitations, especially in progressive or advanced cases. Recent advancements in corneal stromal regeneration offer promising alternatives for enhancing vision restoration and halting disease progression.
View Article and Find Full Text PDFLipidomics reveals the lipid-lowering and hepatoprotective effects of Celosia Semen on high-fat diet-induced NAFLD mice.
J Ethnopharmacol
January 2025
State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing, 211198, China. Electronic address:
Article Synopsis
- Celosia Semen (CS) is a traditional Chinese medicine known for promoting liver health and improving vision, primarily due to its active components, particularly triterpenoid saponins like Celosin I, which are being studied for their effects on non-alcoholic fatty liver disease (NAFLD).
- The study aims to explore the therapeutic effects of total saponins from CS (TSCS) and Celosin I (CI) on NAFLD, using a combination of in vitro and in vivo approaches to understand their molecular mechanisms and health benefits.
- Results showed that TSCS and CI significantly reduced lipid accumulation and liver injury caused by a high-fat diet, improved lipid metabolism by correcting dysregulation linked to NAFL
Spatially Selective Retinal Ganglion Cell Activation Using Low Invasive Extraocular Temporal Interference Stimulation.
Int J Neural Syst
January 2025
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.
Article Synopsis
- - This study explores the use of Temporal Interference Stimulation (TIS) as a noninvasive method for visual restoration, contrasting with traditional retinal implants that require complex surgeries.
- - An improved model of TIS demonstrated that optimal placement of electrodes and specific stimulation parameters can enhance the activation of retinal ganglion cells (RGCs), leading to better visual outcomes.
- - Key findings showed that TIS outperformed traditional sinusoidal stimulation by lowering activation thresholds and enabling precise targeting of RGCs, suggesting a promising new approach to vision restoration.
Network meta-analysis of the efficacy of physical exercise interventions on vision health in children and adolescents.
Front Public Health
September 2024
The School of Physical Education and Sports, Central China Normal University, Wuhan, China.
Objective: This study systematically evaluates the impact of different physical exercise modalities on vision health interventions for Chinese children and adolescents.
Methods: A comprehensive search was conducted in databases, including Web of Science, PubMed, EBSCO, MEDLINE, Embase, and CNKI. The focus was on randomized controlled trial (RCT) studies related to physical activity interventions for vision health in this demographic.
Small-Incision new generation implantable miniature telescope surgical technique and patient outcomes.
Eur J Ophthalmol
May 2024
Department of Biomedical Sciences, Humanitas University, Milano, Italy.
Background: Various ocular implants were suggested as a means of enhancing vision in patients with advanced age related macular degeneration. Recently, a new generation of implantable telescopes has been released. The purpose of this study is to report the surgical technique of implantation along with patient outcomes.
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