Molecular Imaging of Recurrent and Metastatic Prostate Cancer.

Semin Nucl Med

The Department of Molecular Imaging and Therapeutic Nuclear Medicine, the Peter MacCallum Cancer Centre, Melbourne, Australia; The Uro-Oncology Service, the Peter MacCallum Cancer Centre, Melbourne, Australia; The Sir Peter MacCallum Department of Oncology, the University of Melbourne, Parkville, Australia. Electronic address:

Published: July 2019

Although bone-scanning agents remain important for the detection of bone metastasis, the most common site of distant disease in prostate cancer, novel molecular imaging techniques are entering into clinical practice that provide new opportunities to both detect and characterize sites of involvement by prostate cancer, particularly in the setting of recurrent or advanced metastatic disease based on biochemical, clinical or imaging criteria. These approaches can define disease burden, guide locoregional salvage therapies, and select and monitor systemic treatment. While a wide array of tracers is available, the clinical role of broad classes of agents will be reviewed. An exciting and emerging role of molecular imaging is its use in selecting patients for radionuclide therapy.

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http://dx.doi.org/10.1053/j.semnuclmed.2019.02.005DOI Listing

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