AI Article Synopsis
- * Results indicated a significant association where higher vitamin B6 intake was linked to a 35% reduced risk of pancreatic carcinoma (RR 0.65, 95% CI: 0.53-0.80), indicating no significant differences among the studies analyzed.
- * The analysis suggested that while vitamin B6 could lower pancreatic cancer risk, further research is needed due to limitations in the current findings.
Article Abstract
There are conflicting results for the association between vitamin B6 intake with reduced pancreatic carcinoma risk. Thus, a meta-analysis was performed to summarize the evidences from epidemiological studies. We searched documents from PubMed-Medline, Web of Science, and Cochrane Library. The results were analyzed by using Stata software. A total of nine studies were included. The multivariate-adjusted results found that the total RR values of pancreatic carcinoma was 0.65 (95% CI: 0.53-0.80) for the highest vitamin B6 intake vs the lowest vitamin B6 intake, and there was no significant heterogeneity among studies ( = 42.0%, = 0.087). Sensitivity analysis indicated that no single study leaded to an excessive change for the relation between vitamin B6 intake and pancreatic carcinoma risk. This meta-analysis suggested that vitamin B6 intake could significantly decrease pancreatic carcinoma risk. However, further study is needed based on the limitations of the current analysis.
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| http://dx.doi.org/10.1080/01635581.2019.1598562 | DOI Listing |
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